| Identification | Back Directory | [Name]
5-Bromo-thiophene-2-carboxylic acid methyl ester | [CAS]
62224-19-5 | [Synonyms]
5-broMo-
Methyl 2-broMothiophene-5...
2-Bromo-5-(methoxycarbonyl)thiophene
Methyl 2-broMothiophene-5-carboxylate
Methyl 5-bromo-2-thiophenecarboxylate
methyl 5-bromothiophene-2-carboxylate
5-bromo-2-thiophenecarboxylic acid methyl ester
5-Bromo-thiophene-2-carboxylic acid methyl ester
2-Thiophenecarboxylic acid, 5-bromo-, methyl ester | [Molecular Formula]
C6H5BrO2S | [MDL Number]
MFCD03233845 | [MOL File]
62224-19-5.mol | [Molecular Weight]
221.07 |
| Chemical Properties | Back Directory | [Melting point ]
87-88℃ | [Boiling point ]
251.9±20.0 °C(Predicted) | [density ]
1.662±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,2-8°C |
| Hazard Information | Back Directory | [Uses]
Methyl 5-Bromo-2-thiophenecarboxylate is used as a reagent in the synthesis of trisubstituted isoxazole derivatives which are novel nonsteroidal antagonists of Farnesoid X Receptor (FXR). FXR plays an important role in regulation of cholesterol, lipid and glucose metabolism. | [Synthesis Reference(s)]
Journal of Medicinal Chemistry, 35, p. 1109, 1992 DOI: 10.1021/jm00084a016 |
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