| Identification | Back Directory | [Name]
LFM-A13 | [CAS]
62004-35-7 | [Synonyms]
LFM-A13
2-CYANO-N-(2,5-DIBROMOPHENYL)-3-HYDROXY-2-BUTENAMIDE
2-Cyano-N-(2,5-dibromophenyl)-3-hydroxybut-2-enamide
2-Cyano-N-(2,5-dibromophenyl)-3-hydroxy-2-buteneamide
2-Butenamide, 2-cyano-N-(2,5-dibromophenyl)-3-hydroxy-
2-Cyano-3-hydroxy-but-2-enoic acid (2,5-dibromo-phenyl)-amide
ALPHA-CYANO-BETA-HYDROXY-BETA-METHYL-N-(2,5-DIBROMOPHENYL)PROPENAMIDE | [Molecular Formula]
C11H8Br2N2O2 | [MDL Number]
MFCD02179204 | [MOL File]
62004-35-7.mol | [Molecular Weight]
360 |
| Hazard Information | Back Directory | [Uses]
LFM-A13 is a novel anti-leukemic agent targeting Bruton''s tyrosine kinase (BTK). LFM-A13 is a BTK inhibitor. | [Biological Activity]
Potent and selective inhibitor of Bruton's tyrosine kinase (BTK). Inhibits recombinant BTK with an IC 50 value of 2.5 μ M and has no activity on other protein kinases ( including JAK1, JAK3, HCK, EGFR kinase and insulin receptor kinase) at concentrations of up to 278 μ M. | [storage]
Store at RT |
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| Company Name: |
TCI Europe
|
| Tel: |
320-37350700 |
| Website: |
https://www.tcichemicals.com/de/de/index.html |
| Company Name: |
TCI AMERICA
|
| Tel: |
800-4238616 |
| Website: |
https://www.tcichemicals.com/en/us/index.html |
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