Identification | Back Directory | [Name]
Cyclic AMP | [CAS]
60-92-4 | [Synonyms]
CAMP Acrasin 3:5-CAMP CYCLIC AMP 3',5'-cAMPH cyclic3’,5’-amp CYCLIC AMP-3',5' 3',5'-CYCLIC AMP 5’-cyclicmonophosphate ADENOSINE CYCLPHOSPHATE Adenosin Cyclophosphate adenosine3’,5’-phosphate ADENOSINE CYCLOPHOSPHATE cyclic3’,5’-adenylicacid ADENOSINE CYCLICPHOSPHATE Adenosine 3',5'-phosphate Cyclic 3',5'-adenylic acid 3',5'-Cyclic AMP
3',5'-cAMP adenosinecyclicmonophosphate ADENOSINE 3'5'-MONOPHOSPHATE adenosine3’,5’-cyclophosphate cyclicadenosine3’,5’-phosphate adenosinecyclic3’,5’-phosphate Adenosine cyclic monophosphate Adenosine 3',5'-cyclophosphate Adenosine cyclic 3',5'-phosphate Cyclic adenosine 3',5'-phosphate ADENOSINE-3':5'-PHOSPHATE CYCLIC ADENOSINE-3':5'-CYCLIC PHOSPHATE adenosinecyclicphosphate,cyclicamp 3',5'-Cyclic adenylphosphoric acid Adenosine 3',5'-hydrogen phosphate Adenosine-3',5'-cyclophosphate ,99% 3'-5' Cyclic adenosine monophosphate Cyclic adenosine 3',5'-monophosphate Adenosine cyclic 3',5'-monophosphate ADENOSINE-3',5'-CYCLIC PHOSPHATE H2O ADENOSINE-3',5'-CYCLOPHOSPHORIC ACID ADENOSINE 3':5'-CYCLIC MONOPHOSPHATE ADENOSINE 3'-,5'-CYCLIC MONOPHOSPHATE Adenosine-3'',5''-monophosphoric acid adenosine 3',5'-phosphate monohydrate Cyclic Adenosine Monophosphate (cAMP) Adenosine-3’,5’-cyclic phosphoric acid (-)-ADENOSIN-3',5'-CYCLOPHOSPHORSAEURE 9 cyclic3’,5’-(hydrogenphosphate)-adenosin (-)-ADENOSINE 3',5'-CYCLIC MONOPHOSPHATE adenosine,cyclic3’,5’-(hydrogenphosphate) ADENOSINE-3',5'-CYCLIC-MONOPHOSPHORIC ACID ADENOSINE-3':5'-CYCLIC MONOPHOSPHORIC ACID cyclic 3',5'-(hydrogen phosphate)Adenosine CAMP, ADENOSINE-3',5'-CYCLIC MONOPHOSPHATE Adenosine 3'-,5'-cyclic monophosphate, 99+% Adenosine 3',5'-Cyclic Monophosphate Hydrate Adenosine, cyclic 3',5'-(hydrogen phosphate) ADENOSINE 3':5'-CYCLIC MONOPHOSPHATEFREE ACID Monoclonal Anti-cAMP antibody produced in mouse (S)-CYCLIC 3' 5'-(HYDROGEN PHOSPHATE) ADENOSINE Adenosine 3',5'-cyclic Monophosphate Monohydrate ADENOSINE 3':5'-CYCLIC MONOPHOSPHATE*HPL C MARKER CYCLIC-AMP (ADENOSINE 3'', 5''-CYCLIC MONOPHOSPHATE) 3μ,5μ-Cyclic AMP, Adenosine 3μ,5μ-cyclophosphate, cAMP ADENOSINE-3,5-CYCLICMONOPHOSPHPRIC ACID extrapure for biochemistry 6-(6-Amino-9H-purin-9-yl)tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine-2,7-diol 2-oxide | [EINECS(EC#)]
200-492-9 | [Molecular Formula]
C10H12N5O6P | [MDL Number]
MFCD00005845 | [MOL File]
60-92-4.mol | [Molecular Weight]
329.21 |
Hazard Information | Back Directory | [Chemical Properties]
White crystalline powder | [Definition]
ChEBI: A 3',5'-cyclic purine nucleotide having having adenine as the nucleobase. | [Uses]
cAMP is used for intracellular signal transduction in many different organisms, conveying the cAMP-dependent pathway. Restoration of several morphological characteristics of normal fibroblasts in sarcoma cells when treated with adenosine-3?: 5?-cyclic monophosphate. In the presence of adenosine 3?:5?-cyclic monophosphate, protein kinase I dissociated into two subunits: a subunit binding adenosine 3?:5?-cyclic monophosphate, and a catalytic subunit. Stimulation of calcium uptake in platelet membrane vesicles by adenosine 3?,5?-cyclic monophosphate. | [General Description]
Cyclic AMP is a second messenger molecule comprised of an adenine ribonucleotide bearing a phosphate group bound to the oxygen molecules at the 3' and 5' positions of the sugar moiety. Cyclic AMP, which is synthesized from ATP by the intracellular enzyme adenylate cyclase, modulates the activity of several hormone-dependent signal transduction pathways. | [Biochem/physiol Actions]
Naturally-occurring activator of cyclic-AMP-dependent protein kinase (PKA). cAMP is an important second messenger that is linked in many systems to neurotransmitter- or hormone-induced receptor stimulation. The cAMP/PKA signaling pathway has been shown to inhibit cell proliferation, induce differentiation and lead to apoptosis. | [Safety Profile]
Human mutation data reported.When heated to decomposition it emits toxic fumes ofPOx and NOx. | [Synthesis]
Cyclic AMP is synthesized from ATP by adenylate cyclase located on the inner side of the plasma membrane and anchored at various locations in the interior of the cell.[1] Adenylate cyclase is activated by a range of signaling molecules through the activation of adenylate cyclase stimulatory G (Gs)-protein-coupled receptors. Adenylate cyclase is inhibited by agonists of adenylate cyclase inhibitory G (Gi)-protein-coupled receptors. Liver adenylate cyclase responds more strongly to glucagon, and muscle adenylate cyclase responds more strongly to adrenaline. cAMP decomposition into AMP is catalyzed by the enzyme phosphodiesterase. |
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