| Identification | Back Directory | [Name]
6,7-DIHYDROXY-1-METHYL-1,2,3,4-TETRAHYDROISOQUINOLINE HYDROBROMIDE | [CAS]
59709-57-8 | [Synonyms]
rac Salsolinol, HydrobroMide
(R,S)-Salsolinol hydrobromide
(+/-)-SALSOLINOL, HYDROBROMIDE
1,2,3,4-Tetrahydro-1-methyl-6,7-Isoquinolinediol
1-METHYL-6,7-DIHYDROXY-1,2,3,4-TETRAHYDROISOQUINOLINE
6,7-DIHYDROXY-1-METHYL-1,2,3,4-TETRAHYDROISOQUINOLINE
1-methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline HBr
1,2,3,4-TETRAHYDRO-1-METHYL-6,7-ISOQUINOLINEDIOL HYDROBROMIDE
1,2,3,4-Tetrahydro-1-methylisoquinoline-6,7-diol hydrobromide
1-Methyl-1,2,3,4-tetrahydroisoquinoline-6,7-diol·hydrobrominate
1-METHYL-6,7-DIHYDROXY-1,2,3,4-TETRAHYDROISOQUINOLINE HYDROBROMIDE
6,7-DIHYDROXY-1-METHYL-1,2,3,4-TETRAHYDROISOQUINOLINE HYDROBROMIDE
1,2,3,4-Tetrahydro-1-methyl-6,7-Isoquinolinediol hydrobromide (1:1)
6,7-Dihydroxy-1-methyl-1,2,3,4-tetrahydroisoquinoline hydrobromide,98%
6,7-DIHYDROXY-1-METHYL-1,2,3,4-TETRAHYDROISOQUINOLINE HYDROBROMIDE 98%
1-Methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline 1,2,3,4-Tetrahydro-1-methylisoquinoline-6,7-diol hydrobromide | [Molecular Formula]
C10H14BrNO2 | [MDL Number]
MFCD00012741 | [MOL File]
59709-57-8.mol | [Molecular Weight]
260.13 |
| Chemical Properties | Back Directory | [Appearance]
Off-White Powder | [Melting point ]
186-187 °C(lit.)
| [storage temp. ]
Hygroscopic, -20?C Freezer, Under Inert Atmosphere | [solubility ]
H2O: soluble5mg/mL (warmed; clear solution) | [form ]
powder | [color ]
white to brown | [Stability:]
Store in freezer at -20°C |
| Hazard Information | Back Directory | [Chemical Properties]
Off-White Powder | [Uses]
Salsolinol is derived from the neurotransmitter dopamine and acetaldehyde. Interest in this molecule comes from studies suggesting that it might be involved in alcohol addiction, as acetaldehyde is both a well recognized substrate for the Pictet-Spengler reaction and the primary metabolite of ethanol in the liver. It has further been suggested that acetaldehyde formed as a result of alcohol consumption might induce central changes in the metabolism of dopamine. | [Definition]
ChEBI: 1-methyl-1,2,3,4-tetrahydroisoquinoline-6,7-diol hydrobromide is a hydrobromide. It contains a 1-methyl-1,2,3,4-tetrahydroisoquinoline-6,7-diol. | [General Description]
Salsolinol (6,7-dihydroxy-1-methyl-1,2,3,4-tetrahydroisoquinoline) is present in various edibles. It is available as?R?and?S?enantiomers. R-salsolinol in predominantly found in the brain tissue of humans. | [Biochem/physiol Actions]
Salsolinol, a neurotoxin, can serve as a prolactin-releasing factor and an etiological factor in the tuberoinfundibular pathway and in Parkinson′s disease (PD), respectively. It can also act as a modulator of catecholaminergic neurotransmission in the nigrostriatal pathway. In central nervous system, salsolinol can change the role of dopaminergic neurons and dopamine metabolism. |
| Spectrum Detail | Back Directory | [Spectrum Detail]
6,7-DIHYDROXY-1-METHYL-1,2,3,4-TETRAHYDROISOQUINOLINE HYDROBROMIDE(59709-57-8)MS
6,7-DIHYDROXY-1-METHYL-1,2,3,4-TETRAHYDROISOQUINOLINE HYDROBROMIDE(59709-57-8)1HNMR
6,7-DIHYDROXY-1-METHYL-1,2,3,4-TETRAHYDROISOQUINOLINE HYDROBROMIDE(59709-57-8)13CNMR
6,7-DIHYDROXY-1-METHYL-1,2,3,4-TETRAHYDROISOQUINOLINE HYDROBROMIDE(59709-57-8)IR1
6,7-DIHYDROXY-1-METHYL-1,2,3,4-TETRAHYDROISOQUINOLINE HYDROBROMIDE(59709-57-8)IR2
|
|
| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
|