| Identification | Back Directory | [Name]
TRISIALOGANGLIOSIDE GT1B 3NA | [CAS]
59247-13-1 | [Synonyms]
GT1B 3NA
Aids002547
Aids-002547
Ganglioside G1
ganglioside,gt1
GT1B-GANGLIOSIDE
GT1B (NH4+ SALT)
GANGLIOSIDE-GT1B
GT1b-Ganglioside sodium
TRISIALOGANGLIOSIDE GT1B
GT1b-Ganglioside ammonium
TRISIALOGANGLIOSIDE GT1B 3NA
Ganglioside GT1b (sodium salt)
TRISIALOGANGLIOSIDE GT1B, HUMAN
IV3NEUAC, II3(NEUAC)2-GGOSE4CER
GANGLIOSIDE GT1B TRISODIUM SALT
Ganglioside gt1B polysaccharide
TRISIALOGANGLIOSIDE GT1B, BOVINE
GT1b-Ganglioside (triammonium salt)
TRISIALOGANGLIOSIDE GT1B (NH4+ SALT)
(ganglioside gt1B) from bovine brain
Ganglioside GT1b Mixture (sodium salt)
TRISIALOGANGLIOSIDE GT1B 3NA USP/EP/BP
MONOSIALOGANGLIOSIDE GT1B TRISODIUM SALT
GANGLIOSIDEGT1BTRISODIUMSALT,BOVINEBRAIN
trisialoganglioside-gt1b from bovine brain
Trisialoganglioside-GT1b, 96%, from bovine brain
Ganglioside GT1b Mixture (bovine) (ammonium salt)
Ganglioside GT1b Mixture (porcine) (ammonium salt)
Trisialoganglioside GT1b, Bovine Brain (NH4+ salt)
Ganglioside GT1b Mixture sodium salt (Ganglioside G1 Mixture) | [Molecular Formula]
C95H162N5Na3O47 | [MDL Number]
MFCD00081622 | [MOL File]
59247-13-1.mol | [Molecular Weight]
2195.28 |
| Hazard Information | Back Directory | [Chemical Properties]
lyophilized powder | [Uses]
Ganglioside GT1b trisodium salt (bovine brain) is a glycosphingolipid neuroprotectant. | [Uses]
Gangliosides are formed from a glycosphingolipid combined with one or more sialic acids at the oligosaccharide chain. They are anchored at the outer surface of the plasma membrane where they pack densely with cholesterol to form lipid microdomains that modulate both intra- and inter-cellular signaling events. Ganglioside GT1b is a trisialoganglioside that is characterized by having two sialic residues linked to the inner galactose unit. Ganglioside GT1b has inhibitory effects towards human humoral immune responses. At 0.1-10 μM, it can inhibit spontaneous IgG, IgM, and IgA production by human peripheral blood mononuclear cells. It has also been proposed as a host cell receptor for the Merkel cell polyomavirus and as a means to enable the initiation of an infection leading to Merkel cell carcinoma.[Cayman Chemical] | [General Description]
Ganglioside GT1b is a brain ganglioside. It is composed of a neutral tetra-saccharide core, with one or two sialic acid on the internal galactose and an extra sialic acid on the non-reducing terminal of galactose. | [storage]
Store at -20°C |
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