| Identification | Back Directory | [Name]
(7R)-6,7,7a,8-Tetrahydro-7-acetyl-5H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline | [CAS]
5894-74-6 | [Synonyms]
VLT043
(-)-N-Acetylanonaine
(7R)-6,7,7a,8-Tetrahydro-7-acetyl-5H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline
Ethanone, 1-[(7aR)-5,6,7a,8-tetrahydro-7H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinolin-7-yl]- | [Molecular Formula]
C19H17NO3 | [MOL File]
5894-74-6.mol | [Molecular Weight]
307.34 |
| Hazard Information | Back Directory | [Description]
Anemonin, a naturally occurring selective iNOS inhibitor, it has potential anti-inflammatory effect.
Anemonin is a potent protective molecule for osteoarthritis, it delays osteoarthritis progression by suppressing ECM loss and chondrocyte hypertrophy partially by suppressing IL-1β/NF-κB pathway activation.
3. Anemonin can alleviate nerve injury after cerebral ischemia and reperfusion (i/r) in rats by improving antioxidant activities and inhibiting apoptosis pathway.
4. Anemonin inhibits melanin synthesis by inhibiting the transcription of the genes encoding MITF, TYR, TRP1, and TRP | [Definition]
ChEBI: N-Acetylanonaine is an isoquinoline alkaloid. | [target]
NOS | IL Receptor | NF-kB | MMP(e.g.TIMP) |
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