| Identification | Back Directory | [Name]
2-(3,4-dihydroxyphenyl)acetaldehyde | [CAS]
5707-55-1 | [Synonyms]
Dopal (>
Dopal (>80%)
3,4-Dihydroxyphenylacetaldehyde
2-(3,4-dihydroxyphenyl)acetaldehyde
Benzeneacetaldehyde, 3,4-dihydroxy-
Droxidopa Impurity 2Q: What is
Droxidopa Impurity 2 Q: What is the CAS Number of
Droxidopa Impurity 2 Q: What is the storage condition of
Droxidopa Impurity 2 Q: What are the applications of
Droxidopa Impurity 2 | [Molecular Formula]
C8H8O3 | [MDL Number]
MFCD19707262 | [MOL File]
5707-55-1.mol | [Molecular Weight]
152.15 |
| Chemical Properties | Back Directory | [Boiling point ]
350.9±27.0 °C(Predicted) | [density ]
1.306±0.06 g/cm3(Predicted) | [storage temp. ]
Hygroscopic, -20°C Freezer, Under inert atmosphere | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
9.62±0.10(Predicted) | [color ]
Pale Brown to Very Dark Brown | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Uses]
Dopal is a product of Dopamine (CAT# D533780) catabolism by monoamine oxidase and may be further oxidized to 3,?4-?Dihydroxyphenylacetic Acid (CAT# D454250) via aldehyde dehydrogenase. DOPAL can also be reduced to Hydroxy Tyrosol (CAT# H977000) via cytosolic aldehyde or aldose reductase. DOPAL is harmful to nigrostriatal DA terminals and contributes to the profound putamen DA deficiency found in Parkinson''s disease. Cytosolic and mitochondrial aldehyde dehydrogenase (ALDH) isoenzymes deficiency in mice results in increased levels of DOPAL, causing neurodegeneration and motor dysfunction also associated with Parkinson''s disease. | [Uses]
Dopal is the reactive metabolite of dopamine (D533780), an endogenous catecholamine with α and β-adrenergic activity. | [Definition]
ChEBI: A phenylacetaldehyde in which the 3 and 4 positions of the phenyl group are substituted by hydroxy groups. |
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