| Identification | Back Directory | [Name]
4-METHYLPYRAZOLE HYDROCHLORIDE | [CAS]
56010-88-9 | [Synonyms]
FOMEPIZOLE HYDROCHLORIDE
4-METHYLPYRAZOLE HYDROCHLORIDE
Fomepizole/FomepizolechlorideHCl
4-Methyl-1H-pyrazole hydrochloride
4-Methylpyrazole hydrochloride alcohol dehydrogenase inhibitor | [Molecular Formula]
C4H7ClN2 | [MDL Number]
MFCD00012707 | [MOL File]
56010-88-9.mol | [Molecular Weight]
118.56 |
| Hazard Information | Back Directory | [Uses]
4-Methylpyrazole hydrochloride has been used:
- as a cytochrome P450 2E1 inhibitor
- as cytochrome P450 2E1 and alcohol dehydrogenase inhibitor in 1C11 neural progenitor cells
- to inhibit ethanol oxidation in VL-17A cells expressing alcohol dehydrogenase and HepG2 cells
| [Biochem/physiol Actions]
4-Methylpyrazole (4MP) inhibits ethanol oxidation in liver microsomes. It also blocks the c-Jun N-terminal kinase (JNK) activation in in vitro liver injury models. |
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| Company Name: |
Spectrum Chemical Manufacturing Corp.
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021-021-021-67601398-809-809-809 15221380277 |
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www.spectrumchemical.com/oa_html/index.jsp?minisite=10020&respid=22372&language=us |
| Company Name: |
SynAsst Chemical.
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021-60343070 |
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| Company Name: |
Sigma-Aldrich
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021-61415566 800-8193336 |
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https://www.sigmaaldrich.cn |
| Company Name: |
Energy Chemical
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021-58432009 400-005-6266 |
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http://www.energy-chemical.com |
| Company Name: |
SIGMA-RBI
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| Tel: |
800 736 3690 (Orders) |
| Website: |
www.sigma-aldrich.com |
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