| Identification | Back Directory | [Name]
6-CHLORO-3,4-DIHYDRO-3-[(2-PROPENYLTHIO)METHYL]-2H-1,2,4-BENZOTHIADIAZINE-7-SULFONAMIDE 1,1-DIOXIDE | [CAS]
5588-16-9 | [Synonyms]
P-1779
Altizid
CB 8093
CB-8093
Althizide
ALTHIAZIDE
Altizide CRS
Altizide (Y0000606)
3-[(Allylthio)methyl]-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
3-[(allylthio)methyl]-6-chloro-1,1-diketo-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide
3-((allylthio)methyl)-6-chloro-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide 1,1-dioxide
6-CHLORO-3,4-DIHYDRO-3-[(2-PROPENYLTHIO)METHYL]-2H-1,2,4-BENZOTHIADIAZINE-7-SULFONAMIDE 1,1-DIOXIDE
6-chloro-1,1-dioxo-3-(prop-2-enylsulfanylmethyl)-3,4-dihydro-2H-1λ6,2,4-benzothiadiazine-7-sulfonamide
6-Chloro-3,4-dihydro-3-[(2-propen-1-ylthio)Methyl]-2H-1,2,4-benzothiadiazine-7-sulfonaMide 1,1-Dioxide
6-chloro-1,1-dioxo-3-(prop-2-enylsulfanylmethyl)-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide
2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-3-[(2-propen-1-ylthio)methyl]-, 1,1-dioxide
(3RS)-6-Chloro-3-[(prop-2-enylsulfanyl)methyl]-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
6-chloro-1,1-dioxo-3-(prop-2-enylsulfanylmethyl)-3,4-dihydro-2H-1λ6,2,4-benzothiadiazine-7-sulfonamide | [EINECS(EC#)]
226-994-8 | [Molecular Formula]
C11H14ClN3O4S3 | [MDL Number]
MFCD00063558 | [MOL File]
5588-16-9.mol | [Molecular Weight]
383.89 |
| Hazard Information | Back Directory | [Description]
Althiazide, also known as altizide, is an agent belonging to the class of thiazide diuretics with antihypertensive activity. This aldosterone antagonist is often combined with spironolactone. | [Chemical Properties]
White Solid | [Originator]
Althiazide,Solchem | [Uses]
Diuretic and antihypertensive. | [Definition]
ChEBI: 6-chloro-1,1-dioxo-3-[(prop-2-enylthio)methyl]-3,4-dihydro-2H-1$l^{6},2,4-benzothiadiazine-7-sulfonamide is a benzothiadiazine. | [Manufacturing Process]
To 6.75 g (0.0225 mole) of 4-amino-2-chloro-5-(methylsulfamyl)
benzenesulfonamide in 45 ml of dimethylformamide is added 4.86 g (0.03
mole) of dimethyl allylmercaptoacetal followed by 1.5 ml ethyl acetate
saturated with hydrogen chloride gas. The solution is refluxed for 1.5 hours,
cooled and added dropwise with stirring to ice/water. The resulting precipitate
is filtered, dried and recrystallized from isopropanol. The recrystallization gave
4.0 g of 2-methyl-3-allylthiomethyl-6-chloro-7-sulfamyl-3,4-dihydro-1,2,4-
benzothiadiazine-1,1-dioxide; M.P. 168.5-170°C. | [Therapeutic Function]
Diuretic, Antihypertensive |
|
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Cochemical Ltd.
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029-86115547 17791676824 |
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www.cochemical.com |
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Energy Chemical
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021-58432009 400-005-6266 |
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http://www.energy-chemical.com |
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