| Identification | Back Directory | [Name]
VER-49009 | [CAS]
558640-51-0 | [Synonyms]
CS-2575
CCT 129397
VER-49009;VER 49009;VER49009
5-(5-Chloro-2,4-dihydroxyphenyl)-N-ethyl-4-(4-methoxyphenyl)-1H-pyrazole-3-carboxamide
1H-Pyrazole-3-carboxamide, 5-(5-chloro-2,4-dihydroxyphenyl)-N-ethyl-4-(4-methoxyphenyl)- | [EINECS(EC#)]
604-604-1 | [Molecular Formula]
C19H18ClN3O4 | [MOL File]
558640-51-0.mol | [Molecular Weight]
387.82 |
| Chemical Properties | Back Directory | [Boiling point ]
620.2±55.0 °C(Predicted) | [density ]
1.379±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 100 mg/mL (257.85 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble) | [form ]
Powder | [pka]
7.86±0.25(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
VER 49009 is a heat shock protein 90 (HSP90) inhibitor. VER 49009 causes induction of HSP72 and HSP27 alongside depletion of client proteins, including C-RAF, B-RAF, and survivin, and the protein arginine methyltransferase PRMT5. | [Definition]
ChEBI: 5-(5-chloro-2,4-dihydroxyphenyl)-N-ethyl-4-(4-methoxyphenyl)pyrazole-3-carboxamide is an aromatic amide obtained by formal condensation of the carboxy group of 5-(5-chloro-2,4-dihydroxyphenyl)-4-(4-methoxyphenyl)pyrazole-3-carboxylic acid with the amino group of ethylamine. It has a role as a Hsp90 inhibitor. It is a member of pyrazoles, a member of resorcinols, a member of monochlorobenzenes, a monomethoxybenzene and an aromatic amide. | [storage]
Store at -20°C |
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| Company Name: |
SPIRO PHARMA
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| Tel: |
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www.spiropharma.com.cn |
| Company Name: |
Musechem
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+1-800-259-7612 |
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www.musechem.com |
| Company Name: |
DC Chemicals
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021-58447131 13564518121 |
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http://www.approvedhomemanagement.com/ShowSupplierProductsList927327/0.htm |
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