Identification | Back Directory | [Name]
trichodesmine | [CAS]
548-90-3 | [Synonyms]
(3R,4R,5R,8a1R,13aR)-4,5-dihydroxy-3-isopropyl-4,5-dimethyl-4,5,8,8a1,10,12,13,13a-octahydro-2H-[1,6]dioxacycloundecino[2,3,4-gh]pyrrolizine-2,6(3H)-dione 2H-[1,6]Dioxacycloundecino[2,3,4-gh]pyrrolizine-2,6(3H)-dione, 4,5,8,10,12,13,13a,13b-octahydro-4,5-dihydroxy-4,5-dimethyl-3-(1-methylethyl)-, (3R,4R,5R,13aR,13bR)- | [Molecular Formula]
C18H27NO6 | [MDL Number]
MFCD00871305 | [MOL File]
548-90-3.mol | [Molecular Weight]
353.412 |
Chemical Properties | Back Directory | [Melting point ]
160-161 °C (decomp) | [Boiling point ]
546.5±50.0 °C(Predicted) | [density ]
1.29±0.1 g/cm3(Predicted) | [pka]
12.19±0.60(Predicted) |
Hazard Information | Back Directory | [Uses]
Trichodesmine is a pyrrolizidine alkaloid that has neurotoxic effects and is naturally found in Crotolaria argyptiaca, a shrub plant that is native to the south eastern desert of Egypt. Trichodesmine is also known to have toxic effects on pyrrole binding and Glutathione (G597951) metabolism in the rat. |
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