| Identification | Back Directory | [Name]
JNK INHIBITOR II, NEGATIVE CONTROL | [CAS]
54642-23-8 | [Synonyms]
SAPK INHIBITOR II
SP 600125, negative control
N1-METHYL-1,9-PYRAZOLOANTHRONE
N'-METHYL-1,9-PYRAZOLOANTHRONE
JNK INHIBITOR II, NEGATIVE CONTROL
2-Methyldibenzo[cd,g]indazol-6(2H)-one
Dibenz[cd,g]indazol-6(2H)-one, 2-methyl-
JNK Inhibitor II, Negative Control - CAS 54642-23-8 - Calbiochem | [Molecular Formula]
C15H10N2O | [MDL Number]
MFCD00446029 | [MOL File]
54642-23-8.mol | [Molecular Weight]
234.25 |
| Hazard Information | Back Directory | [Uses]
JNK inhibitor II, negative control is the methylated analog of JNK inhibitor II and exhibits a lower affinity for JNK2 and JNK3. This compound is suitable to be used as a negative control in various kinase assays. | [General Description]
A useful negative control for JNK Inhibitor II (SP600125, Cat. No. 420119). Inhibits JNK2 and JNK3 only at much higher concentrations (IC50 = 18 μM and 24 μM, respectively) compared to SP600125 (IC50 = 40 nM and 90 nM, respectively). | [Biochem/physiol Actions]
Target IC50: 18 μM and 24 μM against JNK2 and JNK3, respectively |
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