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ChemicalBook--->CAS DataBase List--->54635-62-0

54635-62-0

54635-62-0 Structure

54635-62-0 Structure
IdentificationBack Directory
[Name]

EMD 386088 HYDROCHLORIDE
[CAS]

54635-62-0
[Synonyms]

EMD 386088 hydrochlo
EMD 386088 HYDROCHLORIDE
5-Chloro-2-methyl-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole
5-Chloro-2-methyl-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-indole
1H-Indole, 5-chloro-2-methyl-3-(1,2,3,6-tetrahydro-4-pyridinyl)-
5-Chloro-2-methyl-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indolehydrochloride
[Molecular Formula]

C14H15ClN2
[MDL Number]

MFCD09038557
[MOL File]

54635-62-0.mol
[Molecular Weight]

246.74
Chemical PropertiesBack Directory
[Boiling point ]

438.1±45.0 °C(Predicted)
[density ]

1.242±0.06 g/cm3(Predicted)
[storage temp. ]

Desiccate at RT
[pka]

16.73±0.30(Predicted)
Hazard InformationBack Directory
[Definition]

ChEBI: 5-chloro-2-methyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole is a member of indoles.
[Biological Activity]

Potent 5-HT 6 receptor agonist (EC 50 = 1.0 nM) that displays selectivity over other 5-HT receptors (IC 50 values are 7.4, 110, 180, 240, 450, 620, 660 and 3000 nM for 5-HT 6 , 5-HT 1D , 5-HT 1B , 5-HT 2A , 5-HT 2C , 5-HT 4 , 5-HT 1A and 5-HT 7 receptors respectively). Shows moderate affinity at 5-HT 3 receptors (IC 50 = 34 nM).
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