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ChemicalBook--->CAS DataBase List--->54397-85-2

54397-85-2

54397-85-2 Structure

54397-85-2 Structure
IdentificationBack Directory
[Name]

THROMBOXANE B2
[CAS]

54397-85-2
[Synonyms]

TXB2
THROMBOXANE B2
Thromboxane B2 EIA
TXB2 (Thromboxane B2)
Thromboxane B2 MaxSpecStandard
Thromboxane B2 Lipid Maps MS Standard
9ALPHA,11,15S-TRIHYDROXYTHROMBA-5Z,13E-DIEN-1-OIC ACID
(5Z,13E,15S)-9α,11,15-Trihydroxythromboxa-5,13-dien-1-oic acid
(5Z,9α,13E,15S)9,11,15-TrihydroxythroMboxa-5,13-dien-1-oic Acid
(5Z,9α,13E,15S)-9,11,15-Trihydroxythromboxa-5,13-diene-1-oic acid
(5z,9α,11rs,13e,15s)-9,11,15-trihydroxythromboxa-5,13-dien-1-oic acid
[5Z,9ALPHA,11RS,13E,15S]-9,11,15-TRIHYDROXYTHROMBOXA-5,13-DIEN-1-OIC ACID
TXB2, (5Z,9α,11RS,13E,15S)-9,11,15-Trihydroxythromboxa-5,13-dien-1-oic acid
8-(1-Hydroxy-3-oxopropyl)-9,12-dihydroxy-5,10-heptadecadienoic Acid HeMiacetal
(E)-7-[(2S,3S,4S)-4,6-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]oxan-3-yl]hept-5-enoic acid
(5Z)-7-[(2R,3S,4S)-Tetrahydro-4,6-dihydroxy-2-[(1E,3S)-3-hydroxy-1-octenyl]-2H-pyran-3-yl]-5-heptenoic Acid
5-Heptenoic acid, 7-[(2R,3S,4S)-tetrahydro-4,6-dihydroxy-2-[(1E,3S)-3-hydroxy-1-octen-1-yl]-2H-pyran-3-yl]-, (5Z)-
[Molecular Formula]

C20H34O6
[MDL Number]

MFCD00135258
[MOL File]

54397-85-2.mol
[Molecular Weight]

370.48
Chemical PropertiesBack Directory
[Melting point ]

95-96°
[alpha ]

D25 +57.4° (c = 0.26 in ethyl acetate)
[storage temp. ]

−20°C
[solubility ]

Chloroform (Slightly, Heated)
[form ]

Solid
[color ]

White to Off-White
[Merck ]

13,9466
Safety DataBack Directory
[Hazard Codes ]

Xn,T
[Risk Statements ]

63-52/53-34-32-23/24/25-5
[Safety Statements ]

22-36-45-36/37/39-26
[WGK Germany ]

3
[F ]

8-10-21
Hazard InformationBack Directory
[Chemical Properties]

White Solid
[Uses]

An inactive metabolite/product of Thromboxane A2 (TBXA2): a compound involved in platelet activation and aggregation in case of a wound. Urinary analysis of TXB2 accurately reflects intrarenal TXA2 synthesis while measurement of 11-dehydro TBX2 (D230555) and 2,3-dinor thromboxane metabolites gives the best estimate of systemic TXA2 secretion.
[Uses]

TXB2 is a stable, biologically inert metabolite formed from the non-enzymatic hydrolysis of TXA2, which has a half-life of about 30 seconds. Urinary analysis of TXB2 accurately reflects intrarenal TXA2 synthesis, while measurement of 11-dehydro and 2,3-dinor thromboxane metabolites gives the best estimate of systemic TXA2 secretion.
[Definition]

ChEBI: A member of the class of thromboxanes B that is (5Z,13E)-thromboxa-5,13-dien-1-oic acid substituted by hydroxy groups at positions 9, 11 and 15.
[storage]

Store at -20°C
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