| Identification | Back Directory | [Name]
3,4-DIHYDRO-2H-PYRIDO[1,2-A]PYRIMIDIN-2-ONE | [CAS]
5439-14-5 | [Synonyms]
ACID CAPTOR H
LABOTEST-BB LT00847264
Dihydropyridopyrimidinone
3,4-dihydropyrido[1,2-a]pyrimidin-2-one
3,4-DIHYDRO-2-PYRIDOL[1,2-A]PYRIMIDINONE
3,4-DIHYDRO-2H-PYRIDO[1,2-A]PYRIMIDIN-2-ONE
2H-Pyrido[1,2-a]pyrimidin-2-one,3,4-dihydro-
3,4-Dihydro-2H-pyrido[1,2-a]pyrimidin-2-one >
3,4-Dihydro-2iHi-pyrido[1,2-iai]pyrimidin-2-one
3,4-DIHYDRO-2H-PYRIDO[1,2-A]PYRIMIDIN-2-ONE 98+%
3,4-DIHYDRO-2H-PYRIDO[1,2-A]PYRIMIDIN-2-ONE ISO 9001：2015 REACH | [EINECS(EC#)]
226-618-2 | [Molecular Formula]
C8H8N2O | [MDL Number]
MFCD00042798 | [MOL File]
5439-14-5.mol | [Molecular Weight]
148.16 |
| Chemical Properties | Back Directory | [Melting point ]
185-187 °C
| [Boiling point ]
271℃ | [density ]
1.26 | [Fp ]
118℃ | [storage temp. ]
2-8°C
| [solubility ]
Chloroform (Sparingly), Methanol (Slightly) | [form ]
Solid | [pka]
2.83±0.20(Predicted) | [color ]
Light Yellow | [BRN ]
3667723 |
| Hazard Information | Back Directory | [Preparation]
3,4-Dihydro-2h-pyrido[1,2-a]pyrimidin-2-one is prepared by reaction of 2-aminopyridine with either Acrylic Acid itself or an equivalent (2-bromo- or 2-iodopropionic acid, Methyl Acrylate, ethyl 2-bromopropionate, β- Propiolactone). | [storage]
The reagent may be dried over P2O5 in vacuo (135 °C/17 mmHg). | [Purification Methods]
Dissolve it in CHCl3, filter, evaporate, then recrystallise the residue from EtOH/Me2CO (needles) which can be washed with Et2O and dried. It can also be recrystallised from CHCl3/pet ether or CHCl3/hexane. The hydrochloride has m 295-295o (dec, from EtOH or MeOH/Et2O), the hydrobromide has m 299-300o(dec) (from MeOH/Et2O) and the picrate has m 224-226o(corr), m 219-220o from EtOH. [Adams & Pachter J Am Chem Soc 74 4906 1952, Lappin J Org Chem 23 1358 1958, Hurd & Hayao J Am Chem Soc 77 115 1955, Beilstein 24 III/IV 299.] |
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| Company Name: |
Energy Chemical
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| Tel: |
021-021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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