| Identification | Back Directory | [Name]
CAULOPHYLLOGENIN | [CAS]
52936-64-8 | [Synonyms]
Segetalic acid
CAULOPHYLLOGENIN
CAULOPHYLLOGENIN hplc
CAULOPHYLLOGENIN WITH HPLC
3β,16α,23-Trihydroxyoleana-12-ene-28-oic acid
(4R)-3β,16α,23-Trihydroxyolean-12-en-28-oic acid
3BETA,16ALPHA,23-TRIHYDROXYYOLEAN-12-ENE 28-OIC-ACID
3BETA, 16ALPHA, 23-TRIHYDROXYOLEAN-12-ENE 28-OIC ACID
(3β,4α,16α)-3,16,23-trihydroxyolean-12-en-28-oic acid
(3beta,4alpha,16alpha)-3,16,23-trihydroxyolean-12-en-28-oic acid | [EINECS(EC#)]
258-265-5 | [Molecular Formula]
C30H48O5 | [MDL Number]
MFCD00017384 | [MOL File]
52936-64-8.mol | [Molecular Weight]
488.7 |
| Chemical Properties | Back Directory | [Melting point ]
>300°C (dec.) | [Boiling point ]
621.5±55.0 °C(Predicted) | [density ]
1.19±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [pka]
4.42±0.70(Predicted) | [LogP]
5.930 (est) |
| Hazard Information | Back Directory | [Description]
Caulophyllogenin is an important commercial chemical that is widely used in the manufacture of rubber hardeners, electroplating additives, skin antiseptic bactericides, hair dyes, photographic developers, etc. Pesticide intermediates of propoxur and carbocarb. | [Chemical Properties]
Caulophyllogenin is an important commercial chemical that is widely used in the manufacture of rubber hardeners, electroplating additives, skin antiseptic bactericides, hair dyes, photographic developers, etc. Pesticide intermediates of propoxur and carbocarb. | [Uses]
Caulophyllogenin is a triterpene saponin extracted from M. polimorpha. Caulophyllogenin is a partial PPARγ agonist, with an EC50?of?12.6?μM. Caulophyllogenin can be used for the research of type-2 diabetes, obesity, metabolic syndrome and inflammation[1][2]. | [Definition]
ChEBI: Caulophyllogenin is a triterpenoid. | [Biological Activity]
Caulophyllogenin is a triterpenoid saponin extracted from M. polimorpha. It is a partial agonist of PPARγ with an EC50 value of 12.6 μM. Caulophyllogenin can be used to study type 2 diabetes, obesity, metabolic syndrome and inflammation. | [IC 50]
PPARγ: 12.6 μM (EC50) | [storage]
Store at -20°C | [References]
[1] Montanari R, et, al. Screening of saponins and sapogenins from Medicago species as potential PPARγ agonists and X-ray structure of the complex PPARγ/caulophyllogenin. Sci Rep. 2016 Jun 10; 6:27658. DOI:10.1038/srep27658
[2] Zhang Y, et, al. Studies on cytotoxic triterpene saponins from the leaves of Aralia elata. Food Chem. 2013 May 1;138(1):208-13. DOI:10.1016/j.foodchem.2012.10.041 |
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