| Identification | Back Directory | [Name]
(1R,1'R,2S,2'S)-DUANPHOS | [CAS]
528814-26-8 | [Synonyms]
(1R,1'R,2S,2'S)- 2,2'-bis(1,1-diMethylethyl)-2,2',3,3'-tetrahydro-1,1'-Bi-1H-isophosphindole
(1R,1'R,2S,2'S)-2,2'-Bis(1,1-dimethylethyl)-2,2',3,3'-tetrahydro-1,1'-bi-1H-isophosphindole,99%e.e. | [Molecular Formula]
C24H32P2 | [MDL Number]
MFCD07781993 | [MOL File]
528814-26-8.mol | [Molecular Weight]
382.465 |
| Chemical Properties | Back Directory | [Melting point ]
214-246 °C | [alpha ]
+19.5 | [Boiling point ]
474.5±45.0 °C(Predicted) | [form ]
crystal | [color ]
white | [optical activity]
[α]20/D +18°, c = 1 in chloroform | [Sensitive ]
air sensitive | [CAS DataBase Reference]
528814-26-8 |
| Questions And Answer | Back Directory | [Reactions]
- As a highly electron-donating and conformationally rigid ligand, the rhodium complex of DuanPhos has exhibited remarkably high enantioselectivities and reactivities for the hydrogenation of a variety of functionalized olefins.
- Rhodium/DUANPHOS catalyst used in the synthesis of 2-trifluoromethyl lactic acid by asymmetric hydroformylation.
|
| Hazard Information | Back Directory | [Uses]
Chiral Quest Phosphine Ligands for Asymmetric Hydrogenation
Catalytic ligand used for:
- Stereoselective synthesis of cyano-substituted dihydropyrroles by annulation of cyanoallenes
- Rhodium-catalyzed intermolecular enantioselective hydroacylation of alkynes to give alpha- and beta-substituted unsaturated ketones by kinetic resolution
- Stereoselective preparation of β-amino nitriles via rhodium-catalyzed asymmetric hydrogenation of amino acrylonitriles
- Stereoselective preparation of anti-1,3-amino alcohols via rhodium-catalyzed asymmetric hydrogenation of β-ketoenamide intermediates
- Stereoselective preparation of acetylaminoindane via rhodium-catalyzed asymmetric hydrogenation of acetylaminoindene
| [General Description]
(1R,1′R,2S,2′S)-DuanPhos is an electron-rich chiral phosphine ligand mainly for transition metal catalyzed asymmetric hydrogenation. |
|
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Sigma-Aldrich Gold
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