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ChemicalBook--->CAS DataBase List--->51230-19-4

51230-19-4

51230-19-4 Structure

51230-19-4 Structure
IdentificationBack Directory
[Name]

PYR-HIS-TRP-SER-TYR-D-ALA-LEU-ARG-PRO-GLY-NH2
[CAS]

51230-19-4
[Synonyms]

TAP 142
wy-18186
(D-ALA6)-LHRH
(D-ALA8) LHRH
(d-ala(sup6))-lhrh
[D-ALA6]-LH-RH (HUMAN)
[d-ala6]-lh-rh acetate hydrate
(D-Ala6)-GnRH, (D-Ala6)-Gonadorelin
[D-Ala6]-LH-RH acetate salt hydrate
[D-Ala6]-LH-RH hydrate acetate salt
(D-ALA6)-GONADOTROPIN-RELEASING HORMONE
(D-ALA6)-LUTEINIZING HORMONE-RELEASING FACTOR
GLP-HIS-TRP-SER-TYR-D-ALA-LEU-ARG-PRO-GLY-NH2
PYR-HIS-TRP-SER-TYR-D-ALA-LEU-ARG-PRO-GLY-NH2
(D-ALA6)-LUTEINIZING HORMONE-RELEASING HORMONE
(d-ala(sup6))-luteinizinghormone-releasinghormon
(d-ala(sup6))-luteinizinghormone-releasinghormone
PYROGLU-HIS-TRP-SER-TYR-D-ALA-LEU-ARG-PRO-GLY NH2
(D-Ala6)-LHRH (D-Ala6)-GnRH, (D-Ala6)-Gonadorelin
[D-ALA6]-LUTEINIZING HORMONE-RELEASING HORMONE (HUMAN)
Luteinizing hormone-releasing factor (swine), 6-D-alanine-
(D-Ala6)-LHRH acetate salt Pyr-His-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-Gly-NH2 acetate salt
[Molecular Formula]

C56H77N17O13
[MDL Number]

MFCD00133502
[MOL File]

51230-19-4.mol
[Molecular Weight]

1196.32
Chemical PropertiesBack Directory
[density ]

1.52±0.1 g/cm3(Predicted)
[storage temp. ]

−20°C
[pka]

9.82±0.15(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]


GHS08
[Signal word ]

Danger
[Hazard statements ]

H360
[Precautionary statements ]

P201-P308+P313
[Hazard Codes ]

T
[Risk Statements ]

60
[Safety Statements ]

53-22-36/37/39-45
[WGK Germany ]

3
[RTECS ]

OK6400000
Hazard InformationBack Directory
[Uses]

[D-Ala6]-LH-RH acetate salt hydrate has been used to induce ovulation and to synchronize the reproductive cycle in Sprague-Dawley female rats.
[Biochem/physiol Actions]

(D-Ala6)-LH-RH is a GnRH (gonadotropin-releasing hormone) agonist. GnRH, which is also referred to as LHRH (luteinizing hormone-releasing hormone) or gonadorelin, is crucial for mammalian reproduction and is released from hypothalamic neurons. It is responsible for the secretion of gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), from pituitary glands. Mutations in GnRH are associated with normosmic congenital hypogonadotropic hypogonadism.
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