Identification | Back Directory | [Name]
PYR-HIS-TRP-SER-TYR-D-ALA-LEU-ARG-PRO-GLY-NH2 | [CAS]
51230-19-4 | [Synonyms]
TAP 142 wy-18186 (D-ALA6)-LHRH (D-ALA8) LHRH (d-ala(sup6))-lhrh [D-ALA6]-LH-RH (HUMAN) [d-ala6]-lh-rh acetate hydrate (D-Ala6)-GnRH, (D-Ala6)-Gonadorelin [D-Ala6]-LH-RH acetate salt hydrate [D-Ala6]-LH-RH hydrate acetate salt (D-ALA6)-GONADOTROPIN-RELEASING HORMONE (D-ALA6)-LUTEINIZING HORMONE-RELEASING FACTOR GLP-HIS-TRP-SER-TYR-D-ALA-LEU-ARG-PRO-GLY-NH2 PYR-HIS-TRP-SER-TYR-D-ALA-LEU-ARG-PRO-GLY-NH2 (D-ALA6)-LUTEINIZING HORMONE-RELEASING HORMONE (d-ala(sup6))-luteinizinghormone-releasinghormon (d-ala(sup6))-luteinizinghormone-releasinghormone PYROGLU-HIS-TRP-SER-TYR-D-ALA-LEU-ARG-PRO-GLY NH2 (D-Ala6)-LHRH
(D-Ala6)-GnRH, (D-Ala6)-Gonadorelin [D-ALA6]-LUTEINIZING HORMONE-RELEASING HORMONE (HUMAN) Luteinizing hormone-releasing factor (swine), 6-D-alanine- (D-Ala6)-LHRH acetate salt Pyr-His-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-Gly-NH2 acetate salt | [Molecular Formula]
C56H77N17O13 | [MDL Number]
MFCD00133502 | [MOL File]
51230-19-4.mol | [Molecular Weight]
1196.32 |
Hazard Information | Back Directory | [Uses]
[D-Ala6]-LH-RH acetate salt hydrate has been used to induce ovulation and to synchronize the reproductive cycle in Sprague-Dawley female rats. | [Biochem/physiol Actions]
(D-Ala6)-LH-RH is a GnRH (gonadotropin-releasing hormone) agonist. GnRH, which is also referred to as LHRH (luteinizing hormone-releasing hormone) or gonadorelin, is crucial for mammalian reproduction and is released from hypothalamic neurons. It is responsible for the secretion of gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), from pituitary glands. Mutations in GnRH are associated with normosmic congenital hypogonadotropic hypogonadism. |
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