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ChemicalBook--->CAS DataBase List--->51116-01-9

51116-01-9

51116-01-9 Structure

51116-01-9 Structure
IdentificationBack Directory
[Name]

8-BROMOGUANOSINE 3',5'-(CYCLIC) MONOPHOSPHATESODIUM SALT N-HYDRATE
[CAS]

51116-01-9
[Synonyms]

BR-CGMP, NA
8-BR-CGMP NA
8-BROMO-CGMP NA
Einecs 256-993-8
8-BROMO-CGMP SODIUM
8-BR-CGMP SODIUM SALT
(115974-70-4) 8-AET-cGMP
8-BROMO-CGMP, SODIUM SALT
8-bromo-Cyclic GMP (sodium salt)
8-BROMOGUANOSINE-3',5'-CYCLOPHOSPHATE SODIUM
8-BROMO-CGMP SODIUM SALT 8-BROMOGUANOSIN E-3',5
8-bromoguanosine 3:5-cyclic*monophosphate sodiu
8-BROMOGUANOSINE-3',5'-CYCLOPHOSPHATE SODIUM SALT
8-BROMOGUANOSINE 3':5'-CYCLICMONOPHOSPHA TE SODIUM
8-Bromoguanosine-3,5-cyclomonophosphate sodium salt
8-BROMOGUANOSINE CYCLIC 3',5'-MONOPHOSPHATE SODIUM SALT
8-BROMOGUANOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
GUANOSINE 3',5'-CYCLIC MONOPHOSPHATE, 8-BROMO-, SODIUM SALT
8-BROMOGUANOSINE-3,5-CYCLICMONOPHOSPHATESODIUMSALT,ULTRAPURE
8-bromoguanosine-3’,5’-cyclicmonophosphate(8-br-cgmp),sodiumsalt,
8-BROMOGUANOSINE 3',5'-(CYCLIC) MONOPHOSPHATESODIUM SALT N-HYDRATE
Guanosine, 8-bromo-, cyclic 3',5'-(hydrogen phosphate), monosodium salt
Guanosine 3,5-cyclic Monophosphate, 8-Bromo-, Sodium Salt - CAS 51116-01-9 - Calbiochem
[EINECS(EC#)]

256-993-8
[Molecular Formula]

C10H10BrN5O7P.Na
[MDL Number]

MFCD03703483
[MOL File]

51116-01-9.mol
[Molecular Weight]

446.08
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[solubility ]

H2O: 100 mg/mL
[form ]

powder
[color ]

White to off-white
[Water Solubility ]

Soluble to 100 mM in water
Safety DataBack Directory
[WGK Germany ]

3
[F ]

10-21
[HS Code ]

29349990
Hazard InformationBack Directory
[Description]

8-bromo-Cyclic GMP (8-bromo-cGMP) is a cell-permeable analog of cGMP that exhibits greater resistance to hydrolysis by phosphodiesterases than its parent compound. It preferentially activates cGMP-dependent protein kinase. At 1 μM-0.1 mM, 8-bromo-cGMP can inhibit acetylcholine-induced increases in intracellular calcium concentrations.
[Chemical Properties]

White powder
[Uses]

8-bromo-cGMP activates cGMP-dependent protein kinase. It can also inhibit acetylcholine-induced increases in intracellular calcium concentrations.
[Definition]

ChEBI: Sodium 8-bromo-3',5'-cyclic GMP is an organic sodium salt having 8-bromoguanosine 3',5'-cyclic phosphate as the counterion. A membrane permeable cGMP analogue that activates protein kinase G (PKG). It is 4.3-fold more potent than cGMP in activating PKG1alpha and promotes relaxation of tracheal and vascular smooth muscle tissue in vitro. It has a role as a protein kinase G agonist and a muscle relaxant. It contains an 8-bromo-3',5'-cyclic GMP(1-).
[Biological Activity]

Membrane permeable cGMP analog that activates protein kinase G (PKG). 4.3-fold more potent than cGMP in activating PKG1 α and promotes relaxation of tracheal and vascular smooth muscle tissue in vitro .
[storage]

Desiccate at -20°C
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