| Identification | Back Directory | [Name]
1-O-HEXADECYL-SN-GLYCEROL | [CAS]
506-03-6 | [Synonyms]
CHIMYL ALCOHOL
1-C16 Ether MG
1-hexadecylglycerol
1-o-hexadecylglycerol
MONOCERYL GLYCERYL ETHER
1-O-PALMITOYL-SN-GLYCEROL
1-O-HEXADECYL-SN-GLYCEROL
α-hexadecylglyceryl ether
3-cetyloxypropane-1,2-diol
3-hexadecoxypropane-1,2-diol
1-O-hexadecyl-sn-glycerol (HG)
3-(hexadecyloxy)-2-propanediol
[S,(+)]-3-O-Hexadecyl-D-glycerol
(S)-3-(hexadecyloxy)propane-1,2-diol
(S)-3-(Hexadecyloxy)-1,2-propanediol
1-O-hexadecyl-sn-glycerol (HG)
1,2-Propanediol, 3-(hexadecyloxy)-, (2S)-
1-O-HEXADECYL-SN-GLYCEROL (HG);1-C16 ETHER MG | [EINECS(EC#)]
208-026-6 | [Molecular Formula]
C19H40O3 | [MDL Number]
MFCD00151171 | [MOL File]
506-03-6.mol | [Molecular Weight]
316.52 |
| Chemical Properties | Back Directory | [Melting point ]
64° | [alpha ]
D20 +3.0° (c = 1.16 in chloroform) | [Boiling point ]
bp0.005 120° | [density ]
1.0054 (rough estimate) | [refractive index ]
1.4410 (estimate) | [storage temp. ]
-15°C | [solubility ]
DMF: 16 mg/ml; DMSO: 0.16 mg/ml; Ethanol: 5 mg/ml | [form ]
A crystalline solid | [pka]
13.68±0.20(Predicted) | [LogP]
6.702 (est) |
| Hazard Information | Back Directory | [Description]
1-O-Hexadecyl-sn-glycerol is a bioactive alkyl glyceryl ether. It reduces UVB-induced cell death and production of reactive oxygen species (ROS) and prostaglandin E2 (PGE2; ) in normal human epidermal keratinocytes (NHEKs). 1-O-Hexadecyl-sn-glycerol (50 μM) increases coronary flow and left ventricular developed pressure and reduces malondialdehyde (MDA) formation ex vivo in a rat heart model of ischemia/reperfusion injury. | [Uses]
1-O-Hexadecyl-sn-glycerol restores plasmalogen levels in Chinese hamster ovary (CHO) cells and human pulmonary arterial endothelial cells (PAEC). Plasmalogen may play a role in protecting animal cells against photosensitized killing. | [Definition]
ChEBI: A 1-n-hexadecyl analogue of an optically active alkylglycerol compound. | [Purification Methods]
Recrystallise it from hexane. [Beilstein 1 III 2322.] |
|
|