| Identification | Back Directory | [Name]
SQ 109 | [CAS]
502487-67-4 | [Synonyms]
SQ 109
NSC 722041
Cenobamate
SQ109 >=98% (HPLC)
SQ109 (NSC 722041)
SQ 109; SQ-109; NSC 722041
N'-(2-adamantyl)-N-[(2E)-3,7-dimethylocta-2,6-dienyl]ethane-1,2-diamine
N-[(2E)-3,7-Dimethyl-2,6-octadienyl]-N'-tricyclo[3.3.1.1(3,7)]dec-2-yl-1,2-ethanediamine
N1-((1R,3S,5r,7r)-adamantan-2-yl)-N2-((E)-3,7-dimethylocta-2,6-dien-1-yl)ethane-1,2-diamine
1,2-Ethanediamine, N1-[(2E)-3,7-dimethyl-2,6-octadien-1-yl]-N2-tricyclo[3.3.1.13,7]dec-2-yl- | [Molecular Formula]
C22H38N2 | [MDL Number]
MFCD11046358 | [MOL File]
502487-67-4.mol | [Molecular Weight]
330.55 |
| Chemical Properties | Back Directory | [Boiling point ]
450.0±33.0 °C(Predicted) | [density ]
0.97±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
Acetone (Slightly), Chloroform (Slightly), Methanol (Slightly) | [form ]
oil | [pka]
9.80±0.20(Predicted) | [color ]
colorless to yellow |
| Hazard Information | Back Directory | [Uses]
SQ109 has been used:
- as an antitubercular?agent to study its interactions with mycobacterial membrane proteins large 3 (MmpL3) binding pocket
- as a positive control to determine the minimum inhibitory concentration (MIC) of ohmyungsamycins (OMS) A and B against Mycobacterium tuberculosis?(Mtb) using the resazurin microtiter assay (REMA) plate method
- as an inhibitor of MmpL3 to explore the utility of mycobacterial CRISPR interference for validating target gene essentiality and compound mode of action
| [General Description]
SQ109 is a 1,2-ethylenediamine, which is related to ethambutol. | [Biochem/physiol Actions]
SQ109 exhibits activity against Helicobacter pylori and the fungi Candida albicans. It might also possess anti-bacterial activity. | [target]
Mycobacterium |
|
| Company Name: |
ChemShuttle, Inc.
|
| Tel: |
0510-83588313-802 18800520310; |
| Website: |
https://www.jiehuapharma.com/ |
| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
SPIRO PHARMA
|
| Tel: |
|
| Website: |
www.spiropharma.com.cn |
|