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ChemicalBook--->CAS DataBase List--->494772-86-0

494772-86-0

494772-86-0 Structure

494772-86-0 Structure
IdentificationBack Directory
[Name]

CAY10657
[CAS]

494772-86-0
[Synonyms]

CAY10657
3-[(AMinocarbonyl)aMino]-5-[4-(4-MorpholinylMethyl)phenyl]-2-thiophenecarboxaMide
3-[(AMinocarbonyl)aMino]-5-[4-(Morpholin-4-ylMethyl)phenyl]thiophene-2-carboxaMide
2-Thiophenecarboxamide, 3-[(aminocarbonyl)amino]-5-[4-(4-morpholinylmethyl)phenyl]-
[Molecular Formula]

C17H20N4O3S
[MDL Number]

MFCD27977686
[MOL File]

494772-86-0.mol
[Molecular Weight]

360.431
Chemical PropertiesBack Directory
[Melting point ]

>200°C (dec.)
[storage temp. ]

Refrigerator
[solubility ]

DMSO (Slightly), Methanol (Slightly, Heated)
[form ]

Solid
[color ]

Pale Yellow to Light Yellow
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501
Hazard InformationBack Directory
[Chemical Properties]

Pale Yellow Solid
[Uses]

3-[(Aminocarbonyl)amino]-5-[4-(4-morpholinylmethyl)phenyl]-2-thiophenecarboxamide is a transforming growth factor (TGF)-β-activated kinase 1 (TAK-1) inhibitor. 3-[(Aminocarbonyl)amino]-5-[4-(4-morphol inylmethyl)phenyl]-2-thiophenecarboxamide has potential use in the treatment of certain lymphomas that are particularly susceptible to TAK1 inhibitors such as B cell tumors, solid tumors, or T cell le ukemias.
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