| Identification | Back Directory | [Name]
LEUCOPTERIN | [CAS]
492-11-5 | [Synonyms]
LEUCOPTERIN
2-aminopteridine-4,6,7-triol
LEUCOPTERIN(RG)(DISCONTINUED)
2-AMINO-4,6,7-TRIHYDROXYPTERIDINE
2-Amino-5,8-dihydropteridine-4,6,7(1H)-trione
2-amino-5,8-dihydro-1H-pteridine-4,6,7-trione
2-azanyl-5,8-dihydro-1H-pteridine-4,6,7-trione | [EINECS(EC#)]
207-747-3 | [Molecular Formula]
C6H5N5O3 | [MDL Number]
MFCD00077935 | [MOL File]
492-11-5.mol | [Molecular Weight]
195.14 |
| Chemical Properties | Back Directory | [Melting point ]
300 °C | [Boiling point ]
331.78°C (rough estimate) | [density ]
1.5875 (rough estimate) | [refractive index ]
1.8500 (estimate) | [solubility ]
Aqueous Base (Slightly) | [form ]
Solid | [pka]
6.74±0.20(Predicted) | [color ]
Pale Beige to Beige | [Water Solubility ]
1.333mg/L(22.5 ºC) |
| Hazard Information | Back Directory | [Uses]
Leucopterin (cas# 492-11-5) is a useful research chemical. It is used in the methods of drug screening to identify compounds for treatment of protein trafficking diseases. | [Definition]
ChEBI: Leucopterin (enol form) is a member of the class of pteridines that is pteridine substituted by an amino group at position 2 and hydroxy groups at positions 4, 6 and 7. It has a role as a biological pigment. It is a member of pteridines, a heteroaryl hydroxy compound and a triol. It is a tautomer of a leucopterin (keto form). | [Purification Methods]
Leucopterin is purified by dissolving it in aqueous NaOH, stirring with charcoal, filtering and precipitating by adding aqueous HCl, then drying at 100o in a vacuum. It separates with 0.5 mole of H2O. Its solubility in H2O is 1g/750 litres [Albert et al. J Chem Soc 4219 1952, Albert & Wood J Appl Chem (London) 2 591 1952, Pfleiderer Chem Ber 90 2631 1957]. [Beilstein 26 III/IV 4017.] |
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