Identification | Back Directory | [Name]
(3S)-3-[[3-[[4-(TRIFLUOROMETHYL)BENZOYL]AMINO]PHENYL]METHOXY]-L-ASPARTIC ACID | [CAS]
480439-73-4 | [Synonyms]
TFB-TBOA TFBTBOA,TFB TBOA (3S)-3-[[3-[[4-(TRIFLUOROMETHYL)BENZOYL]AMINO]PHENYL]METHOXY]-L-ASPARTIC ACID L-Aspartic acid, 3-[[3-[[4-(trifluoromethyl)benzoyl]amino]phenyl]methoxy]-, (3S)- (2S,3S)-2-amino-3-[[3-[[4-(trifluoromethyl)benzoyl]amino]phenyl]methoxy]butanedioic acid | [Molecular Formula]
C19H17F3N2O6 | [MDL Number]
MFCD09971089 | [MOL File]
480439-73-4.mol | [Molecular Weight]
426.34 |
Chemical Properties | Back Directory | [Boiling point ]
513.6±50.0 °C(Predicted) | [density ]
1.500±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble to 100 mM in DMSO | [form ]
Powder | [pka]
2.05±0.27(Predicted) | [color ]
White to off-white |
Hazard Information | Back Directory | [Uses]
TFB-TBOA is a novel glutamate transporter blocker. | [Biological Activity]
High affinity, selective blocker of glial glutamate transporters EAAT1 and EAAT2 (IC 50 values are 17, 22 and 300 nM for EAAT2, EAAT1 and EAAT3 respectively). Displays no activity on a wide range of neurotransmitter receptors and transporters. Induces convulsions following i.c.v. administration in mice. | [storage]
Store at -20°C |
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Company Name: |
BOC Sciences
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Tel: |
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Website: |
https://www.bocsci.com |
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