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ChemicalBook--->CAS DataBase List--->480439-73-4

480439-73-4

480439-73-4 Structure

480439-73-4 Structure
IdentificationBack Directory
[Name]

(3S)-3-[[3-[[4-(TRIFLUOROMETHYL)BENZOYL]AMINO]PHENYL]METHOXY]-L-ASPARTIC ACID
[CAS]

480439-73-4
[Synonyms]

TFB-TBOA
TFBTBOA,TFB TBOA
(3S)-3-[[3-[[4-(TRIFLUOROMETHYL)BENZOYL]AMINO]PHENYL]METHOXY]-L-ASPARTIC ACID
L-Aspartic acid, 3-[[3-[[4-(trifluoromethyl)benzoyl]amino]phenyl]methoxy]-, (3S)-
(2S,3S)-2-amino-3-[[3-[[4-(trifluoromethyl)benzoyl]amino]phenyl]methoxy]butanedioic acid
[Molecular Formula]

C19H17F3N2O6
[MDL Number]

MFCD09971089
[MOL File]

480439-73-4.mol
[Molecular Weight]

426.34
Chemical PropertiesBack Directory
[Boiling point ]

513.6±50.0 °C(Predicted)
[density ]

1.500±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble to 100 mM in DMSO
[form ]

Powder
[pka]

2.05±0.27(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

TFB-TBOA is a novel glutamate transporter blocker.
[Biological Activity]

High affinity, selective blocker of glial glutamate transporters EAAT1 and EAAT2 (IC 50 values are 17, 22 and 300 nM for EAAT2, EAAT1 and EAAT3 respectively). Displays no activity on a wide range of neurotransmitter receptors and transporters. Induces convulsions following i.c.v. administration in mice.
[storage]

Store at -20°C
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