Identification | Back Directory | [Name]
1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[carboxy(polyethylene glycol)-2000] (aMMoniuM salt) | [CAS]
474922-20-8 | [Synonyms]
DSPE-PEG2000-COOH DSPE-PEG-2K-CH2COOH DSPE-PEG(2000) Carboxylic Acid 1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[carboxy(polyethylene glycol)-2000] (aMMoniuM salt) |
Hazard Information | Back Directory | [Description]
DSPE-PEG-CH2COOH, MW 2,000 is a PEG polymer with DSPE and carboxylic acid end groups. The DSPE-PEGs have been FDA approved for medical applications. The hydrophobic properties of the DSPE allow for the encapsulation and congregation of other hydrophobic drugs. The -COOH group can react with primary amines in the presence of activator, such as EDC or HATU, to form a stable amide bond. |
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