| Identification | Back Directory | [Name]
O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine | [CAS]
4604-41-5 | [Synonyms]
3,3'-L-Diiodothyronine
3,3'-Diiodo-L-thyronine
Levothyroxine Impurity 13
Levothyroxine EP Impurity J
3,5-Diiodo-L-tyrosinedihydrae
3-Iodo-O-(4-hydroxy-3-iodophenyl)-L-tyrosine
O-(3-Iodo-4-hydroxyphenyl)-3-iodo-L-tyrosine
O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine
L-Tyrosine,O-(4-hydroxy-3-iodophenyl)-3-iodo-
3-[4-(4-Hydroxy-3-iodophenoxy)-3-iodophenyl]-L-alanine
(S)-α-Amino-4-[(4-hydroxy-3-iodophenyl)oxy]-3-iodobenzenepropanoic acid
(2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3-iodophenyl]propanoic acid
(2S)-2-amino-3-[4-(4-hydroxy-3-iodo-phenoxy)-3-iodo-phenyl]propionic acid
(2S)-2-azanyl-3-[4-(4-hydroxy-3-iodo-phenoxy)-3-iodo-phenyl]propanoic acid | [EINECS(EC#)]
225-005-7 | [Molecular Formula]
C15H13I2NO4 | [MDL Number]
MFCD01863378 | [MOL File]
4604-41-5.mol | [Molecular Weight]
525.077 |
| Chemical Properties | Back Directory | [Appearance]
Off-White Powder | [Melting point ]
178-180°C | [Boiling point ]
520.7±50.0 °C(Predicted) | [density ]
2.095±0.06 g/cm3(Predicted) | [storage temp. ]
Amber Vial, -20°C Freezer, Under Inert Atmosphere | [solubility ]
Aqueous Base (Slightly) | [form ]
Solid | [pka]
2.17±0.20(Predicted) | [color ]
Off-White to Beige | [Stability:]
Light Sensitive |
| Hazard Information | Back Directory | [Chemical Properties]
Off-White Powder | [Uses]
Of interest for the early detection and treatment of congenital or drug-induced hypothyroidism in the developing human fetus | [Description]
3,3''-Diiodo-L-thyronine is a metabolite of thyroid hormone that is also known as T2 or 3,3’-T2.1 It is derived enzymatically from triiodothyronine isoforms T3 and reverse T3. T2 and its analog 3,5-T2 stimulate the activity of cytochrome c oxidase by blocking inhibition by ATP.2,3 | [Definition]
ChEBI: 3,3'-diiodo-L-thyronine is a 3,3'-diiodothyronine. It has a role as a human metabolite. |
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