| Identification | Back Directory | [Name]
NU6140 | [CAS]
444723-13-1 | [Synonyms]
NU6140
4-[[6-(Cyclohexylmethoxy)-1H-purin-2-yl]amino]-N,N-diethylbenzamide
4-[[6-(cyclohexylmethoxy)-7H-purin-2-yl]amino]-N,N-diethylbenzamide
Benzamide, 4-[[6-(cyclohexylmethoxy)-9H-purin-2-yl]amino]-N,N-diethyl- | [Molecular Formula]
C23H30N6O2 | [MDL Number]
MFCD09264153 | [MOL File]
444723-13-1.mol | [Molecular Weight]
422.52 |
| Chemical Properties | Back Directory | [Boiling point ]
707.8±70.0 °C(Predicted) | [density ]
1.234±0.06 g/cm3(Predicted) | [storage temp. ]
Desiccate at +4°C | [solubility ]
DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/ml | [form ]
White to off-white solid. | [pka]
9.41±0.10(Predicted) | [color ]
White to light yellow |
| Hazard Information | Back Directory | [Uses]
NU 6140 is a cyclin-dependant kinase 2 inhibitor which demonstrates 10-36 fold selectivity against Cdk2-cyclin A. This selectivity induces cell-cycle arrest at the G2-M phase and potentiates the apoptotic effect of pacitaxel. | [storage]
Desiccate at +4°C |
|
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
|