Identification | Back Directory | [Name]
Glucagon Receptor Antagonist I | [CAS]
438618-32-7 | [Synonyms]
Glucagon Receptor Antagonist I N-[3-cyano-6-(2-methylbutan-2-yl)-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]-2-ethylbutanamide | [Molecular Formula]
C20H30N2OS | [MDL Number]
MFCD01920208 | [MOL File]
438618-32-7.mol | [Molecular Weight]
346.53 |
Hazard Information | Back Directory | [Description]
Glucagon receptor antagonist I is a competitive antagonist of the glucagon receptor (GCGR; IC50 = 181 nM). It blocks glucagon-induced glycogenolysis in primary human hepatocytes and isolated liver. Glucagon receptor antagonist I, at 50 mg/kg, reduces the increase in glucose levels observed after intraperitoneal administration of glucagon in humanized mice. Glucagon receptor antagonist inactive control does not prevent glucagon-mediated actions. | [storage]
Store at -20°C |
|
Company Name: |
BOC Sciences
|
Tel: |
16314854226 |
Website: |
www.bocsci.com |
Company Name: |
|
Tel: |
4008-099-669 |
Website: |
http://www.approvedhomemanagement.com/ShowSupplierProductsList112975/0.htm |
Company Name: |
EvoBlocks, Ltd.
|
Tel: |
+36 (20) 5757-305 |
Website: |
www.evoblocks.com |
|