| Identification | Back Directory | [Name]
METHYL-D3-MALONIC ACID | [CAS]
42522-59-8 | [Synonyms]
NSC 2520-d3
Isosuccinic Acid-d3
MethylMalonic Acid-d3
METHYL-D3-MALONIC ACID
[2H3]-Methylmalonic Acid
Methyl-d3-propanedioic Acid
2-Methylpropanedioic acid D3
2-METHYL-D3-PROPANEDIOIC ACID
1,1-Ethanedicarboxylic Acid-d3
METHYLMALONIC ACID (METHYL-D3)
Methyl-D3-malonic acid solution
Methylmalonic Acid-[d3] (Solution)
METHYL-D3-MALONIC ACID, 98 ATOM % D | [EINECS(EC#)]
686-010-1 | [Molecular Formula]
C4H3D3O4 | [MDL Number]
MFCD00144783 | [MOL File]
42522-59-8.mol | [Molecular Weight]
121.11 |
| Chemical Properties | Back Directory | [Melting point ]
134-136 °C(lit.) | [Fp ]
2 °C | [storage temp. ]
-20°C | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Chemical Properties]
White to Off-White Solid | [Uses]
An isotope labelled derivative of Methylmalonic Acid (M318860), binds with coenzyme A to form methylmalonyl-CoA, also a metabolic intermediate transformed to succinic acid (SA) by a vitamin B12-dependent catalytic step, and is broadly used as a clinical biomarker of functional vitamin B12 status. | [Uses]
Methyl-d3-malonic acid is an isotope labelled derivative of Methylmalonic Acid (M318860), binds with coenzyme A to form methylmalonyl-CoA, also a metabolic intermediate transformed to succinic acid (SA) by a vitamin B12-depend ent catalytic step, and is broadly used as a clinical biomarker of functional vitamin B12 status.
| [General Description]
Methylmalonic acid, a malonic acid derivative, is a vital intermediate in the metabolism of fat and proteins and plays a key role in energy metabolism. Elevated methylmalonic acid levels can be caused by an inborn error of metabolism leading to methylmalonic aciduria or indicate early vitamin B<sub>12</sub> deficiency. This internal standard is suitable for quantitation of methylmalonic acid levels by LC/MS or GC/MS in newborn screening and clinical testing applications to test for methylmalonic acidemia and diagnose vitamin B<sub>12</sub> deficiency. |
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| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
|