Identification | Back Directory | [Name]
Dihydropleuromutilin | [CAS]
42302-24-9 | [Synonyms]
Azamulin Impurity 1 Dihydropleuromutilin 2-Hydroxy-acetic Acid (3aS,4R,5S,6R,8R,9R,9aR,10R)-6-Ethyldecahydro-5-hydroxy-4,6,9,10-tetraMethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl Ester Acetic acid, 2-hydroxy-, (3aS,4R,5S,6R,8R,9R,9aR,10R)-6-ethyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl ester | [Molecular Formula]
C22H36O5 | [MDL Number]
MFCD28899594 | [MOL File]
42302-24-9.mol | [Molecular Weight]
380.52 |
Chemical Properties | Back Directory | [Melting point ]
141-143°C | [storage temp. ]
Refrigerator | [solubility ]
Chloroform (Slightly), Ethyl Acetate (Slightly) | [form ]
Solid | [color ]
White to Off-White |
Hazard Information | Back Directory | [Description]
Dihydropleuromutilin is a semisynthetic antibiotic and derivative of pleuromutilin . It is active against S. aureus, M. hominis, M. gallisepticum, and M. hyorhinis bacteria (MICs = 0.5, 0.3, 0.3, and 2 μg/ml, respectively). | [Chemical Properties]
White Solid | [Uses]
Dihydropleuromutilin is a semi-synthetic pleuromutilin formed by selective reduction of the ethene to ethyl. Dihydropleuromutilin exhibits comparable antibiotic potency to pleuromutilin. Extensive studies have been undertaken on semi-synthetic dihydropleuromutilin analogues but the parent compound has received only limited attention. | [Uses]
Intermediate in the preparation of Azamulin |
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