Identification | Back Directory | [Name]
1-Bromoethyl acetate | [CAS]
40258-78-4 | [Synonyms]
1-BROMOETHYLACETATE Cefuroxime Impurity 51 1-ACETOXY ETHYL BROMIDE Theophylline Impurity 10 1-Bromoethyl acetate ,90% 1 - broMine ethyl acetate 1-Bromoethyl acetate[BEA] (RS)-1-Acetoxyethyl BroMide Ethanol, 1-bromo-, 1-acetate 1‐Acetoxy?Ethyl?Bromide?(1‐AEB) 1-Acetoxy Ethyl Bromide (1-AEB) CAS No. : 40258-78-4 | [EINECS(EC#)]
609-807-8 | [Molecular Formula]
C4H7BrO2 | [MDL Number]
MFCD08061392 | [MOL File]
40258-78-4.mol | [Molecular Weight]
167 |
Hazard Information | Back Directory | [Chemical Properties]
Pale Yellow Oil | [Uses]
1-Bromoethyl Acetate is a 1-haloalkyl ester that is used in the modification of of antibiotics. | [Synthesis]
1-bromoethyl acetate is prepared by reacting acetyl bromide and acetaldehyde using zinc chloride as a catalyst. After cooling 30 ml of hydrogen bromide / acetic acid (1.2 equiv) to 0 ° C., 53.5 ml (1.0 equiv) of vinyl acetate was slowly added thereto, followed by stirring for 1 hour. It was extracted with dichloromethane, washed with distilled water at 0-5 ° C., dehydrated with anhydrous magnesium sulfate, and distilled under reduced pressure to obtain 81.4 g of 1-bromoethyl acetate.
|
|
|