| Identification | Back Directory | [Name]
3'-BROMO-4'-METHYLACETOPHENONE | [CAS]
40180-80-1 | [Synonyms]
SIPO-022
Fluralaner-004
Siponimod Impurity 1
3'-BROMO-4'-METHYLACETOPHENONE
1-(3-BroMo-4-Methylphenyl)ethanone
3'-Bromo-4'-methylacetophenone 97%
1-(3-Bromo-4-methylphenyl)ethan-1-one
Ethanone, 1-(3-bromo-4-methylphenyl)-
3'-BROMO-4'-METHYLACETOPHENONE ISO 9001：2015 REACH | [Molecular Formula]
C9H9BrO | [MDL Number]
MFCD02683854 | [MOL File]
40180-80-1.mol | [Molecular Weight]
213.07 |
| Chemical Properties | Back Directory | [Melting point ]
42-46 °C(lit.)
| [Boiling point ]
118°C/3mmHg(lit.) | [density ]
1.388±0.06 g/cm3(Predicted) | [storage temp. ]
Inert atmosphere,Room Temperature | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Solid | [color ]
Off-White to Pale Yellow |
| Hazard Information | Back Directory | [Uses]
3''-Bromo-4''-methylacetophenone is used as a starting material in the synthesis of mansonone E which is used to make mansonone E dervivatives. These derivatives are potent inhibitors of topoisomerase II (Topo II) and topoisomerase I (Topo I) and are also potent antitumor agents. 3''-Bromo-4''-methylacetophenone is also used as a reagent in the synthesis of BAF312, Siponimod which has been tested in the treatment of patients suffering from relapsing-remitting multiple sclerosis. |
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