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ChemicalBook--->CAS DataBase List--->39731-05-0

39731-05-0

39731-05-0 Structure

39731-05-0 Structure
IdentificationBack Directory
[Name]

4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1H-INDOLE-2-CARBOXYLIC ACID, 1-METHYLETHYL ESTER
[CAS]

39731-05-0
[Synonyms]

SDZ 21009
Carpindolol
Isopropyl 4-(3-(tert-butylamino)-2-hydroxypropoxy)-1H-indole-2-carboxylate
4-[3-(tert-Butylamino)-2-hydroxypropoxy]-1H-indole-2-carboxylic acid isopropyl ester
4-[3-[(1,1-Dimethylethyl)amino]-2-hydroxypropoxy]-1H-indole-2-carboxylicacid,1-methylethyleste
4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1H-INDOLE-2-CARBOXYLIC ACID, 1-METHYLETHYL ESTER
1H-Indole-2-carboxylic acid, 4-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]-, 1-methylethyl ester
[Molecular Formula]

C19H28N2O4
[MDL Number]

MFCD00869100
[MOL File]

39731-05-0.mol
[Molecular Weight]

348.44
Chemical PropertiesBack Directory
[Boiling point ]

529.8±50.0 °C(Predicted)
[density ]

1.150±0.06 g/cm3(Predicted)
[storage temp. ]

Store at RT
[solubility ]

Soluble to 100 mM in ethanol and to 100 mM in DMSO
[form ]

Powder
[pka]

pKa 8.75 (Uncertain)
Hazard InformationBack Directory
[Uses]

SDZ 21009 is a 5-HT1A/1B antagonist.
[Definition]

ChEBI: 4-[3-(tert-butylamino)-2-hydroxypropoxy]-1H-indole-2-carboxylic acid propan-2-yl ester is an isopropyl ester and an indolyl carboxylate ester.
[Biological Activity]

β -adrenoceptor and 5-HT 1A/1B receptor antagonist. pK B /pA 2 values are 8.3 and 8.0 for 5-HT 1A and 5-HT 1B receptors respectively. Centrally active following systemic administration in vivo .
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