| Identification | Back Directory | [Name]
YE-120 | [CAS]
383124-82-1 | [Synonyms]
YE-120
2-[3-Cyano-5-(3,4-dichloro-phenyl)-4,5-dimethyl-5H-furan-2-ylidene]-malononitrile
2-[3-Cyano-5-(3,4-dichlorophenyl)-4,5-dimethyl-2(5H)-furanylidene]propanedinitrile | [Molecular Formula]
C16H9Cl2N3O | [MOL File]
383124-82-1.mol | [Molecular Weight]
330.17 |
| Chemical Properties | Back Directory | [Boiling point ]
419.1±45.0 °C(Predicted) | [density ]
1.42±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble to 100 mM in DMSO | [form ]
Powder | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
YE-120 is a GPR35 agonist (EC50 = 32 nM in DMR assays). YE-120 also displays partial agonist activity in a β-arrestin translocation assay (EC50 = 10.2 μM). GPR35 is a Class A, rhodopsin-like G protein-coupled receptor which is predominantly expressed in immune and gastrointestinal tissue, with notable expression in the ileum (rat and human GPR35), the spleen (rat and murine GPR35) and the pancreas (human GPR35). | [storage]
Store at -20°C |
|
| Company Name: |
BOC Sciences
|
| Tel: |
|
| Website: |
https://www.bocsci.com |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
cjbscvictory
|
| Tel: |
13348960310 13348960310 |
| Website: |
https://www.weikeqi-biotech.com/ |
| Company Name: |
|
| Tel: |
4008-099-669 |
| Website: |
http://www.approvedhomemanagement.com/ShowSupplierProductsList112975/0.htm |
|