| Identification | Back Directory | [Name]
2-Propenoic acid, 3,3'-(1,3-phenylene)bis- | [CAS]
37710-81-9 | [Synonyms]
TC AQP1 1
2-Propenoic acid, 3,3'-(1,3-phenylene)bis- | [Molecular Formula]
C12H10O4 | [MDL Number]
MFCD00021776 | [MOL File]
37710-81-9.mol | [Molecular Weight]
218.21 |
| Chemical Properties | Back Directory | [Boiling point ]
458.7±33.0 °C(Predicted) | [density ]
1.358±0.06 g/cm3(Predicted) | [storage temp. ]
RT | [solubility ]
Soluble in DMSO (up to 25 mg/ml). | [form ]
solid | [pka]
4.07±0.10(Predicted) | [color ]
White | [Stability:]
Stable for 1 year from date of pruchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months. |
| Hazard Information | Back Directory | [Description]
CVPA (37710-81-9) is an aquaporin-1 inhibitor (IC50 = 8.1 μM) discovered by molecular docking against the extracellular domain of human aquaporin-1 followed by experimental testing in a Xenopus oocyte swelling assay.1 | [Uses]
TC AQP1 1 is a human aquaoporin-1 (hAQP1) selective inhibitor and is considered to have therapeutic potential towards the potential treatment of glaucoma, brain edema, inflammatory pain and certain types of cancer. | [storage]
Store at -20°C | [References]
1) Seeliger et al. (2012), Discovery of novel human aquaporin-1 blockers; ACS Chem. Biol., 8 249 |
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| Company Name: |
BOC Sciences
|
| Tel: |
|
| Website: |
https://www.bocsci.com |
| Company Name: |
InvivoChem
|
| Tel: |
13549236410 |
| Website: |
https://www.invivochem.cn/ |
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