| Identification | Back Directory | [Name]
CAY10602 | [CAS]
374922-43-7 | [Synonyms]
CAY10602
CAY10602 HCl
CAY10602, >98%
SIRT1 Activator II - CAS 374922-43-7 - Calbiochem
Inhibitor,CAY 10602,CAY10602,CAY-10602,inhibit,Sirtuin
1-(4-Fluorophenyl)-3-(phenylsulfonyl)-1H-pyrrolo[2,3-b]quinoxalin-2-amine
1H-Pyrrolo[2,3-b]quinoxalin-2-amine, 1-(4-fluorophenyl)-3-(phenylsulfonyl)- | [Molecular Formula]
C22H15FN4O2S | [MDL Number]
MFCD02236691 | [MOL File]
374922-43-7.mol | [Molecular Weight]
418.444 |
| Chemical Properties | Back Directory | [Melting point ]
270 °C | [storage temp. ]
+2C to +8C | [solubility ]
DMF: 20 mg/ml; DMSO: 20 mg/ml; DMSO:PBS(pH 7.2) (1:3): 0.25 mg/ml | [form ]
Off-white powder | [color ]
Light yellow to Amber to Dark green | [CAS DataBase Reference]
374922-43-7 |
| Hazard Information | Back Directory | [General Description]
A cell-permeable pyrroloquinoxaline compound that acts as a reversible SIRT1 activator (10 μM causes ~2.3-fold fluorescent enhancement in a fluorescent assay using hrSIRT1) and enhances fat mobilization in fully differentiated 3T3L1 fibroblasts. Shown to inhibit LPS-induced TNF-α release in THP-1 cells by ~10-fold more potent than resveratrol (Cat. No. 554325). | [storage]
Store at -20°C |
|
| Company Name: |
TCI Europe
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| Tel: |
320-37350700 |
| Website: |
https://www.tcichemicals.com/de/de/index.html |
| Company Name: |
TCI AMERICA
|
| Tel: |
800-4238616 |
| Website: |
https://www.tcichemicals.com/en/us/index.html |
| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
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