| Identification | Back Directory | [Name]
WILFORGINE | [CAS]
37239-47-7 | [Synonyms]
Wilforgin
WILFORGINE
Aids088959
Aids-088959
4-27-00-06847 (Beilstein Handbook Reference)
8α-acetoxy-O2-(furan-3-carbonyl)-O2-deacetyl-8-deoxo-evonimine
Evonimine, 8-(acetyloxy)-O2-deacetyl-8-deoxo-O2-(3-furanylcarbonyl)-, (8α)-
(8alpha)-8-(Acetyloxy)-O2-deacetyl-8-deoxo-O2-(3-furanylcarbonyl)- evonimine Wilforgin
3-Furancarboxylic acid (8R,9R,10R,11S,12R,13R,14R,15S,18S,21S,22S,23R)-10,13,22,23-tetrakis(acetyloxy)-
3-Furancarboxylic acid, (8R,9R,10R,11S,12R,13R,14R,15S,18S,21S,22S,23R)-10,13,22,23-tetrakis(acetyloxy)-12-[(acetyloxy)methyl]-7,8,9,10,12,13,14,15,17,18,19,20-dodecahydro-21-hydroxy-8,18,21-trimethyl-5,17-dioxo-8,11-epoxy-9,12-ethano-11,15-methano-5H,11H-[1,9]dioxacyclooctadecino[4,3-b]pyridin-14-y...
3-Furancarboxylic acid (8R,9R,10R,11S,12R,13R,14R,15S,18S,21S,22S,23R)-10,13,22,23-tetrakis(acetyloxy)-12-[(acetyloxy)methyl]-7,8,9,10,12,13,14,15,17,18,19,20-dodecahydro-21-hydroxy-8,18,21-trimethyl-5,17-dioxo-8,11-epoxy-9,12-ethano-11,15-methano-5H,11H-[1,9]dioxacyclooctadecino[4,3-b]pyridin-14-yl ester
3-Furancarboxylic acid, 10,13,22,23-tetrakis(acetyloxy)-12-[(acetyloxy)methyl]-7,8,9,10,12,13,14,15,17,18,19,20-dodecahydro-21-hydroxy-8,18,21-trimethyl-5,17-dioxo-8,11-epoxy-9,12-ethano-11,15-methano-5H,11H-[1,9]dioxacyclooctadecino[4,3-b]pyridin-14-yl ester, (8R,9R,10R,11S,12S,13R,14R,15S,18S,21S,22S,23R)- | [Molecular Formula]
C41H47NO19 | [MDL Number]
MFCD01726769 | [MOL File]
37239-47-7.mol | [Molecular Weight]
857.81 |
| Questions And Answer | Back Directory | [Uses]
Wilforgine can be used as lymphocyte immunosuppression, with anti-tumor and anti-inflammatory effects, and can be used for content determination/identification/pharmacological experiments, etc. | [Biological activity]
Wilforgine is a bioactive sesquiterpene alkaloid in Tripterygium wilfordii Hook. F. Wilforgine can induce microstructural and ultrastructural changes in the muscles of Mythimna separata larvae, and the sites of action are proposed to be calcium receptors or channels in the muscular system. |
| Chemical Properties | Back Directory | [Melting point ]
211℃ | [Boiling point ]
859.9±65.0 °C(Predicted) | [density ]
1.43 | [solubility ]
Soluble in methanol; | [form ]
powder | [pka]
11.59±0.70(Predicted) | [color ]
White | [Water Solubility ]
insoluble in water |
| Hazard Information | Back Directory | [Description]
Wilforgine is a alkaloid,it from Tripterygiurn wilfordii Hook forms colourless plates from
MeOH-Me2CO. It is also dextrorotatory having [α]25/sup>D + 25° (Me2CO)。 | [Definition]
ChEBI: A dihydroagarofuran sesquiterpenoid and pyridine alkaloid with formula C41H47NO19 originally isolated from the roots of Tripterygium wilfordii. | [References]
Beroza., J. Arner. Chern. Soc., 74, 1585 (1952)
Beroza., ibid, 75,44 (1953) |
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