| Identification | Back Directory | [Name]
CID 797718 | [CAS]
370586-05-3 | [Synonyms]
CS-1341
CID 797718
CID 797718, >=98%
CID-797718;CID797718
CID 797718, 370586-05-3
9-Hydroxy-1H,2H,3H,4H-chromeno[3,4-b]pyridin-5-one
9-HYDROXY-1,2,3,4-TETRAHYDROCHROMENO[3,4-B]PYRIDIN-5-ONE
9-HYDROXY-3,4-DIHYDRO-1H-CHROMENO[3,4-B]PYRIDIN-5(2H)-ONE | [Molecular Formula]
C12H11NO3 | [MDL Number]
MFCD03006523 | [MOL File]
370586-05-3.mol | [Molecular Weight]
217.22 |
| Chemical Properties | Back Directory | [Melting point ]
213-216 °C(Solv: isopropanol (67-63-0)) | [Boiling point ]
517.6±50.0 °C(Predicted) | [density ]
1.43±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 30 mg/ml; DMSO: 20 mg/ml; Ethanol: 1 mg/ml | [form ]
A crystalline solid | [pka]
9.39±0.20(Predicted) | [color ]
Light brown to brown |
| Hazard Information | Back Directory | [Description]
CID797718 is a protein kinase D1 (PKD1) inhibitor (IC50 = 7 μM). It also inhibits CDK activating kinase (CAK) and polo-like kinase 1 (PLK1) but has no activity at AKT (IC50s = 8.4, 21.9, and >50 μM, respectively). CID797718 inhibits PKD1 activity in LNCaP cells with an IC50 value of 0.21 μM. CID797718 is a byproduct in the synthesis of CID755673 . | [storage]
Store at -20°C |
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