Identification | Back Directory | [Name]
1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE | [CAS]
36507-30-9 | [Synonyms]
C07496 GP 49-023 (11-epoxide-d10) carbamazepineepoxide 10,11-epoxycarbamazepine carbamazepine10,11-oxide CARBAMAZEPINE 10,11-EPOXIDE CarbaMazepine-10,11-epoxide-d10 Carbamazepine-10,11-epoxide solution 10,11-Epoxycarbamazepine (Metabolite) 10,11-Dihydro-10,11-epoxycarbamazepine 1aH-dibenzo[b,f]oxireno[2,3-d]azepine-6(10bH)-carboxaMide f)oxiren(d)azepine-6-carboxamide,1a,10b-dihydro-6h-dibenz( 1a,10b-dihydro-6h-dibenz(b,f)oxiren(d)azepine-6-carboxamide 1a,10b-Dihydro-6H-dibenz[b,f]oxireno[d]azepine-6-carboxamide 6H-Dibenz[b,f]oxireno[d]azepine-6-carboxaMide,1a,10b-dihydro- 1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE 1a,10b-Dihdyro-6H-dibenzo[b,f]oxireno[d]azepine-6-carboxamide 10,11-Dihydro-10,11-epoxy-5H-dibenzo[b,f]azepine-5-carboxamide 1A,10BETA-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE | [EINECS(EC#)]
200-659-6 | [Molecular Formula]
C15H12N2O2 | [MDL Number]
MFCD00467137 | [MOL File]
36507-30-9.mol | [Molecular Weight]
252.27 |
Chemical Properties | Back Directory | [Appearance]
White Solid | [Melting point ]
204-206°C | [Boiling point ]
390.2±52.0 °C(Predicted) | [density ]
1.377±0.06 g/cm3(Predicted) | [Fp ]
9℃ | [storage temp. ]
−20°C
| [solubility ]
Chloroform (Slightly), DMSO (Slightly) | [form ]
neat | [pka]
13.91±0.20(Predicted) | [color ]
White |
Hazard Information | Back Directory | [Chemical Properties]
White Solid | [Uses]
A metabolite of Carbamazepine (C175840).
Representative lots contained 1-2% carbamazepine by HPLC. | [Uses]
A metabolite of Carbamazepine.
Representative lots contained 1-2% carbamazepine by HPLC | [Definition]
ChEBI: An epoxide and metabolite of carbamazepine. | [General Description]
Carbamazepine-10,11-epoxide is the primary, active metabolite in both urine and serum of carbamazepine, an anticonvulsant drug used in the treatment of epilepsy and bipolar disorder as well as trigeminal neuralgia. Potential toxicity of the epoxide metabolite requires regular therapeutic drug monitoring by LC or LC/MS for patients taking carbamazepine. | [Biochem/physiol Actions]
First metabolite of carbamazepine |
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