| Identification | Back Directory | [Name]
Balicatib | [CAS]
354813-19-7 | [Synonyms]
AAE-581
CS-1415
Balicatib
Balicatib, >97%
Balicatib, >=98%
Balicatib, AAE-581
AAE581; AAE 581; AAE-581
N-(1-(CYANOMETHYLCARBAMOYL)CYCLOHEXYL)-4-(4-PROPYLPIPERAZIN-1-YL)BENZAMIDE
Benzamide, N-[1-[[(cyanomethyl)amino]carbonyl]cyclohexyl]-4-(4-propyl-1-piperazinyl)-
N-[1-(Cyanomethylcarbamoyl)cyclohexyl]-4-(4-propylpiperazin-1-yl)benzamide Balicatib(AAE-581)
Balicatib N-[1-(Cyanomethylcarbamoyl)cyclohexyl]-4-(4-propylpiperazin-1-yl)benzamide | [EINECS(EC#)]
200-256-5 | [Molecular Formula]
C23H33N5O2 | [MDL Number]
MFCD19443790 | [MOL File]
354813-19-7.mol | [Molecular Weight]
411.54 |
| Chemical Properties | Back Directory | [Boiling point ]
687.4±55.0 °C(Predicted) | [density ]
1.19±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO:52.04(Max Conc. mg/mL);126.45(Max Conc. mM)
DMF:25.0(Max Conc. mg/mL);60.75(Max Conc. mM)
DMF:PBS (pH 7.2) (1:1):0.5(Max Conc. mg/mL);1.21(Max Conc. mM)
Ethanol:1.75(Max Conc. mg/mL);4.25(Max Conc. mM) | [form ]
A crystalline solid | [pka]
13.23±0.20(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Balicatib is a potent inhibitor of Cathepsin K (Cat K), a lysosomal cysteine protease, for the treatment of osteoporosis. | [storage]
Store at -20°C |
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