| Identification | Back Directory | [Name]
LY 487379 HYDROCHLORIDE | [CAS]
353231-17-1 | [Synonyms]
LY 487379 hydrochlor
LY 487379 HYDROCHLORIDE
2,2,2-trifluoro-N-[4-(2-methoxyphenoxy)phenyl]-N-(3-pyridinylmethyl)ethanesulfonamide
2,2,2-Trifluoro-N-(4-(2-methoxyphenoxy)phenyl)-N-(pyridin-3-ylmethyl)ethanesulfonamide
EthanesulfonaMide, 2,2,2-trifluoro-N-[4-(2-Methoxyphenoxy)phenyl]-N-(3-pyridinylMethyl)-
2,2,2-Trifluoro-N-[4-(2-methoxyphenoxy)phenyl]-N-(3-pyridinylmethyl)ethanesulfonamidehydrochloride | [Molecular Formula]
C21H19F3N2O4S | [MDL Number]
MFCD09475609 | [MOL File]
353231-17-1.mol | [Molecular Weight]
452.45 |
| Chemical Properties | Back Directory | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
DMSO : 100 mg/mL (221.02 mM; Need ultrasonic) | [form ]
Solid | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
LY 487379 Hydrochloride is a group II mGlu receptors activator with anti-hyperthermic effects. Allosteric potentiators of metabotropic glutamate receptor 2 (mGlu2). | [Uses]
LY 487379 is a positive allosteric modulator selective for mGluR-2. | [Biological Activity]
Positive allosteric modulator selective for mGlu 2 receptors. Potentiates glutamate-stimulated [ 35 S]GTP γ S binding (EC 50 values are 1.7 and > 10 μ M for mGlu 2 and mGlu 3 receptors respectively). Devoid of any activity at mGlu 5 and mGlu 7 receptors. |
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| Company Name: |
DC Chemicals
|
| Tel: |
021-58447131 13564518121 |
| Website: |
http://www.approvedhomemanagement.com/ShowSupplierProductsList927327/0.htm |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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