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ChemicalBook--->CAS DataBase List--->3476-50-4

3476-50-4

3476-50-4 Structure

3476-50-4 Structure
IdentificationBack Directory
[Name]

trimethylcolchicinic acid methyl ether
[CAS]

3476-50-4
[Synonyms]

NSC 201400
Deacetylcolchicine
Desacetylcolchicine
Colchicine Impurity 22
(-)-7-Deacetylcolchicine
(S)-N-Deacetyl Colchicine
(-)-N-Deacetyl Colchicine
Colchicine N-Desacetyl (S)-Isomer
trimethylcolchicinic acid methyl ether
7-AMino-6,7-dihydro-1,2,3,10-tetraMethoxy-benzo[a]heptalen-9(5H)-one
(S)-7-Amino-1,2,3,10-tetramethoxy-6,7-dihydrobenzo[a]heptalen-9(5H)-one
(S)-7-Amino-6,7-dihydro-1,2,3,10-tetramethoxybenzo[a]heptalen-9(5H)-one
(7S)-7-Amino-1,2,3,10-Tetramethoxy-6,7-Dihydro-5H-Benzo[g]Heptalen-9-One
(7S)-7-AMino-6,7-dihydro-1,2,3,10-tetraMethoxy-benzo[a]heptalen-9(5H)-one
Benzo[a]heptalen-9(5H)-one, 7-amino-6,7-dihydro-1,2,3,10-tetramethoxy-, (7S)-
[Molecular Formula]

C20H23NO5
[MOL File]

3476-50-4.mol
[Molecular Weight]

357.4
Chemical PropertiesBack Directory
[Boiling point ]

490.03°C (rough estimate)
[density ]

1.2532 (rough estimate)
[refractive index ]

1.5614 (estimate)
[storage temp. ]

-20°C Freezer, Under Inert Atmosphere
[solubility ]

DMSO: 25mg/mL; Ethanol: 25mg/mL
[form ]

A crystalline solid
[pka]

8.62±0.40(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]


GHS05,GHS06,GHS08
[Signal word ]

Danger
[Hazard statements ]

H300-H318-H340
[Precautionary statements ]

P201-P202-P264-P270-P280-P301+P310-P321-P330-P305+P351+P338-P308+P313-P405-P501
Hazard InformationBack Directory
[Chemical Properties]

Yellow Solid
[Uses]

An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.
[Definition]

ChEBI: Deacetylcolchicine is a carbotricyclic compound, an alkaloid and a member of acetamides.
[storage]

Store at -20°C
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