| Identification | Back Directory | [Name]
6-Methylheptanoyl-L-A2bu-L-Thr-L-A2bu-cyclo(L-A2bu*-L-A2bu-D-Phe-L-Leu-L-A2bu-L-A2bu-L-Thr-) | [CAS]
34503-87-2 | [Synonyms]
Polymyxin B2
Unii-99sjo09vh2
polymyxin B2Q: What is
polymyxin B2 Q: What is the CAS Number of
polymyxin B2
6-Methylheptanoyl-L-A2bu-L-Thr-L-A2bu-cyclo(L-A2bu*-L-A2bu-D-Phe-L-Leu-L-A2bu-L-A2bu-L-Thr-)
L-Threonine, N2-(6-methyl-1-oxoheptyl)-L-2,4-diaminobutanoyl-L-threonyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-D-phenylalanyl-L-leucyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-, cyclic (10-4)-peptide
N-[(2S)-4-amino-1-[[(2S,3R)-1-[[(2S)-4-amino-1-oxo-1-[[(3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-15-benzyl-3-[(1R)-1-hydroxyethyl]-12-(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]amino]butan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxobutan-2-yl]-6-methylheptanamide | [Molecular Formula]
C55H96N16O13 | [MOL File]
34503-87-2.mol | [Molecular Weight]
1189.47 |
| Chemical Properties | Back Directory | [alpha ]
225461 -112.4° (2% Acetic acid) | [Boiling point ]
1572.3±65.0 °C(Predicted) | [density ]
1.28±0.1 g/cm3(Predicted) | [solubility ]
Methanol (Slightly), Water (Slightly) | [form ]
Solid | [pka]
13.08±0.70(Predicted) | [color ]
White to Pale Brown | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Uses]
Polymyxin B2 is a cyclic lipopeptide antibiotic. It is a component of Polymyxin B which is used as a last-line treatment for multi-drug resistant gram-negative bacteria. | [Definition]
ChEBI: Polymyxin B2 is a polymyxin having a 6-methylheptanoyl group at the amino terminus. |
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TOSUN PHARM
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www.toref.cn/ |
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