| Identification | Back Directory | [Name]
N-[[[3-[(Benzoyl)amino]phenyl]amino](thioxo)methyl]-3,4,5-trimethoxybenzamide | [CAS]
330829-30-6 | [Synonyms]
MRT-10
MRT-10 >=98% (HPLC)
N-((3-Benzamidophenyl)carbamothioyl)-3,4,5-trimethoxybenzamide
N-({[3-(benzoylamino)phenyl]amino}carbonothioyl)-3,4,5-trimethoxybenzamide
Benzamide, N-[[[3-(benzoylamino)phenyl]amino]thioxomethyl]-3,4,5-trimethoxy-
N-[[[3-[(Benzoyl)amino]phenyl]amino](thioxo)methyl]-3,4,5-trimethoxybenzamide | [Molecular Formula]
C24H23N3O5S | [MDL Number]
MFCD02734587 | [MOL File]
330829-30-6.mol | [Molecular Weight]
465.52 |
| Hazard Information | Back Directory | [Description]
MRT10 is an antagonist of the Smoothened (Smo) receptor with an IC50 value of 0.64 μM in a luciferase reporter assay. It also inhibits bodipy-cyclopamine binding to the murine Smo receptor (IC50 = 0.5 μM) when expressed in HEK293 cells. | [Uses]
MRT 10, is a novel, high-affinity antagonist smoothened (Smo) receptor antagonist. It displaces labeled cyclopamine from Smo with an IC50 of 500 nM, and inhibits shh-induced Gli-reporter activity in Shh-light2 cells (IC50 = 0.64 μM). |
|
| Company Name: |
BOC Sciences
|
| Tel: |
|
| Website: |
https://www.bocsci.com |
| Company Name: |
DC Chemicals
|
| Tel: |
021-58447131 13564518121 |
| Website: |
http://www.approvedhomemanagement.com/ShowSupplierProductsList927327/0.htm |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
|