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ChemicalBook--->CAS DataBase List--->32909-05-0

32909-05-0

32909-05-0 Structure

32909-05-0 Structure
IdentificationBack Directory
[Name]

N4-ACETYL-2'-DEOXYCYTIDINE
[CAS]

32909-05-0
[Synonyms]

ADPN
APM-1
Ac-dC
GBP-28
ADIPOQ
ACRP30
N4-Ac-dC
Adipolean
NAC-2'-DC
N4-Ac-2'-dC
Adipolean (human)
Adiponectin human
ADIPONECTIN mouse
gAcrp30 from mouse
Adiponutrin EIA Kit
Adiponectin from rat
Adiponectin ELISA Kit
Adiponectin from mouse
N4-Acetyldeoxycytidine
gAcrp30/Adipolean human
N-acetyl-2'-deoxycytidine
gAcrp30/Adiponectin human
N4-ACETYL-2'-DEOXYCYTIDINE
ADIPOQ / Adiponectin EIA Kit
gAcrp30/Adiponectin from rat
Cytidine, N-acetyl-2'-deoxy-
Human ADIPOQ Protein, Fc Tag
gAcrp30/Adiponectin from mouse
Adipocyte-specific protein AdipoQ
Human ADIPOQ / Adiponectin ELISA Kit
N4-ACETYL-2'-DEOXYCYTIDINE USP/EP/BP
ANTI-ADIPOQ antibody produced in mouse
30 kDa adipocyte complement-related protein
Adipocyte complement-related 30 kDa protein
Adipose most abundant gene transcript 1 protein
Recombinant Mouse Acrp30/Adipoq Protein, His Tag
Adipocyte, C1q and collagen domain-containing protein
Recombinant Human Adiponectin/ACRP30/ADIPOQ Protein, His Tag
N-[1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-oxopyrimidin-4-yl]acetamide
N-(1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4
N-(1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl
N-(1-((2R,4S,5R)-4-Hydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyriMidin-4-yl)acetaMide
[EINECS(EC#)]

2017-001-1
[Molecular Formula]

C11H15N3O5
[MDL Number]

MFCD00057435
[MOL File]

32909-05-0.mol
[Molecular Weight]

269.25
Chemical PropertiesBack Directory
[Melting point ]

150-152 °C
[density ]

1.60±0.1 g/cm3(Predicted)
[storage temp. ]

Store at 0°C
[solubility ]

DMSO (Slightly, Heated), Methanol (Slightly, Heated, Sonicated), Water (Slightly)
[form ]

lyophilized
[pka]

10.28±0.20(Predicted)
[color ]

White to Off-White
[Stability:]

Hygroscopic
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

36/37/38
[Safety Statements ]

26
[RIDADR ]

UN 3264 8 / PGIII
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

Human ADIPOQ / Adiponectin ELISA Kit has been used in the quantification of leptin and adiponectin from serum and plasma samples.
[Definition]

ChEBI: N(4)-acetyl-2'-deoxycytidine is 2'-deoxyytidine in which one of the exocyclic amino hydrogens is substituted by an acetyl group. It is a secondary carboxamide and a pyrimidine 2'-deoxyribonucleoside.
[General Description]

Rat gAcrp30 (amp-1) is a 16.6 kDa protein that corresponds to the C-terminal globular domain of adiponectin (amp-1). gAcrp30/Adipolean is expressed and secreted exclusively by adipose tissue. This protein possesses unique pharmacological properties for regulation of body weight and lipid metabolism. It is a key component in controlling energy homeostasis. Recently, gAcrp30/Adipolean has been shown to inhibit the proliferation of myelomonocytic progenitors. The Recombinant rat gAcrp30/Adipolean is a 16.6 kDa protein consisting of 145 amino acid residues.
[Biochem/physiol Actions]

In obese mice and humans, adiponectin/gAcrp30 (adipocyte complement-related protein) mRNA expression is reduced, therefore linking this hormone to energy homeostasis. In incubated mouse muscle and cultured cells, gAcrp30 leads to an increase in fatty acid oxidation. This hormone is also linked to anti-atherogenesis, and in apoE-deficient mice, overexpression of gAcrp30 results in significant attenuation of atherosclerosis. Long-term administration of this hormone in mice results in weight loss without reduction in food intake. This hormone is capable of reducing proliferation of MDA-ERα7 cell line. Studies show that ratio of gAcrp30 to leptin and the ERα (estrogen receptor) status of cells are key in determining BRCA (breast cancer) cell growth.
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