Identification | Back Directory | [Name]
CCT020312 | [CAS]
324759-76-4 | [Synonyms]
CCT020312 2(1H)-Quinolinone, 6-bromo-3-[5-(4-bromophenyl)-1-[3-(diethylamino)-1-oxopropyl]-4,5-dihydro-1H-pyrazol-3-yl]-4-phenyl- | [Molecular Formula]
C31H30Br2N4O2 | [MOL File]
324759-76-4.mol | [Molecular Weight]
650.4 |
Chemical Properties | Back Directory | [density ]
1.48±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: soluble | [form ]
A solid | [pka]
9.43±0.70(Predicted) | [color ]
Light yellow to yellow |
Hazard Information | Back Directory | [Biological Activity]
CCT020312 is a selective activator of EIF2AK3/PERK. It induces phosphorylation of EIF2A in cells. | [in vitro]
CCT020312 treatment effectively inhibits cell proliferation (as measured at 96 hours) even if treatment is for 2 hours only with subsequent compound washout, indicating that CCT020312 is capable of eliciting durable rather than transient cytostasis. | [target]
| [storage]
Store at -20°C |
|
Company Name: |
DC Chemicals
|
Tel: |
021-58447131 13564518121 |
Website: |
http://www.approvedhomemanagement.com/ShowSupplierProductsList927327/0.htm |
Company Name: |
MedChemExpress
|
Tel: |
021-58955995 |
Website: |
www.medchemexpress.com |
|