| Identification | Back Directory | [Name]
Ceefourin 1 | [CAS]
315702-40-0 | [Synonyms]
Ceefourin 1
5-[(2-Benzothiazolylthio)methyl]-2,4-dihydro-4-methyl-3H-1,2,4-triazole-3-thione | [Molecular Formula]
C11H10N4S3 | [MOL File]
315702-40-0.mol | [Molecular Weight]
294.42 |
| Chemical Properties | Back Directory | [Melting point ]
181° - 182°C | [Boiling point ]
422.1±55.0 °C(Predicted) | [density ]
1.58±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C, Inert atmosphere | [solubility ]
Chloroform (Slightly), Methanol (Slightly, Heated) | [form ]
Solid | [pka]
8.37±0.20(Predicted) | [color ]
Pale Yellow |
| Hazard Information | Back Directory | [Uses]
Ceefourin 1 inhibit the transport of a broad range of multidrug resistance-associated protein 4 (MRP4). | [Biological Activity]
Ceefourin 1 is a potent and highly selective MRP4 (Multidrug resistance protein 4) inhibitor th at exhibits low cellular toxicity and high microsomal and acid stability. Ceefourin 1 inhibits PDAC (pancreatic ductal adenocarcinoma) cell proliferation through MRP4-dependent cAMP extrusion thereby activation of the cAMP/Epac/Rap1 signaling pathway. | [storage]
Store at -20°C |
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