Identification | Back Directory | [Name]
N-(1,3-benzothiazol-2-yl)-3,3-diphenylpropanamide | [CAS]
313480-47-6 | [Synonyms]
Benzenepropanamide, N-2-benzothiazolyl-β-phenyl- N-(1,3-benzothiazol-2-yl)-3,3-diphenylpropanamide | [Molecular Formula]
C22H18N2OS | [MDL Number]
MFCD01196557 | [MOL File]
313480-47-6.mol | [Molecular Weight]
358.46 |
Hazard Information | Back Directory | [Biological Activity]
IGS-1.76 efficiently inhibits the human NCS-1/Ric8a complex. IGS-1.76 shows a significantly increased affinity for hNCS-1 and is able to modulate the hNCS-1/Ric8a interaction efficiently[1].
IGS-1.76 is a Drosophila NCS-1/IGS-1.76 complex inhibitor[1]. | [storage]
Store at -20°C | [References]
[1]. Carlos Roca, et al. Deciphering the Inhibition of the Neuronal Calcium Sensor 1 and the Guanine Exchange Factor Ric8a with a Small Phenothiazine Molecule for the Rational Generation of Therapeutic Synapse Function Regulators. J Med Chem. 2018 Jul 26;61(14):5910-5921. |
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InvivoChem
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