| Identification | Back Directory | [Name]
N-acetyl aspartyl-glutaMic acid | [CAS]
3106-85-2 | [Synonyms]
NAAG
NAAGA
Naaxia
ZY-15106
ALPHA-NAAG
AC-ASP-GLU
ACETYL-D-E
AC-ASP-GLU-OH
AC-ASP-GLU H2O
SPAGLUMIC ACID
N-ACETYL-ASP-GLU
isospaglumic acid
N-ACETYL-ASP-GLU-OH
NAAG, Spaglumic acid
6-AMINO-1-HEXANETHIOL,HCL
N-ACETYLASPARTYLGLUTAMIC ACID
n-acetyl-1-aspartylglutamicacid
NAAG - CAS 3106-85-2 - Calbiochem
N-ACETYL-L-ASPARTYL-L-GLUTAMIC ACID
N-acetyl aspartyl-glutaMic acid USP/EP/BP
2-[(2-acetamido-3-carboxy-propanoyl)amino]pentanedioic acid
(S)-2-((S)-2-acetaMido-3-carboxypropanaMido)pentanedioic acid | [Molecular Formula]
C11H16N2O8 | [MDL Number]
MFCD00076652 | [MOL File]
3106-85-2.mol | [Molecular Weight]
304.25 |
| Chemical Properties | Back Directory | [Melting point ]
171-173 °C | [Boiling point ]
769.5±60.0 °C(Predicted) | [density ]
1.472±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
H2O: 50 mg/mL
| [form ]
powder
| [pka]
3.04±0.10(Predicted) | [color ]
white
| [optical activity]
[α]22/D 34.5°, c = 1.1 in H2O(lit.) | [Water Solubility ]
Soluble to 100 mM in water | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Chemical Properties]
White powder | [Uses]
N-acetyl aspartyl-glutamic acid is a spaglumic acid is a marker of neuronal integrity and was used in the detection of therapeutic values of antidrepressant treatments.
| [Definition]
ChEBI: A dipeptide composed of N-acetyl-L-aspartic acid and L-glutamic acid joined by a peptide linkage. | [General Description]
NAAG is a neuropeptide and a neurotransmitter that is abundant in the mammalian nervous system. It remains uncertain whether this compound activates NMDA receptors; however, it is clearly demonstrated to act as a selective agonist of mGluR3, both in vitro and in vivo. | [Biochem/physiol Actions]
Endogenous neurotransmitter localized to neurons with high affinity for metabotropic glutamate receptors, mGluR3. It is an antagonist at NMDA receptors. Catabolized by carboxypeptidase II, which is expressed on astrocyte membranes, to N-acetylaspartate and glutamate. | [storage]
Store at -20°C |
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