| Chemical Properties | Back Directory | [Boiling point ]
340.8±52.0 °C(Predicted) | [density ]
1.34±0.1 g/cm3(Predicted) | [storage temp. ]
4°C, protect from light | [solubility ]
Methanol : 250 mg/mL (690.09 mM; Need ultrasonic)|DMSO : 100 mg/mL (276.04 mM; Need ultrasonic) | [form ]
Solid | [pka]
9.56±0.50(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Biological Activity]
BZAD-01 is a potent, selective and orally active inhibitor of NMDA NR2B subunit, with a Ki of 72 nM. BZAD-01 can improve postural asymmetry as well as Apomorphine-induced rotation[1]. | [storage]
4°C, protect from light | [References]
[1]. Truong L, et, al. Behavioural effects of a selective NMDA NR1A/2B receptor antagonist in rats with unilateral 6-OHDA+parafascicular lesions. Brain Res Bull. 2009 Feb 16;78(2-3):91-6. |
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